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GENE：SH3GL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SH3GL1
FullNmae SH3 domain containing GRB2 like 1, endophilin A2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10830
EnsembleID ENSG00000141985
Uniprot Q99961

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SH3GL1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SH3GL1 GO:0002102,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0007165,GO:0007417,GO:0008289,GO:0016191,GO:0031901,GO:0042802,GO:0042995,GO:0045296,GO:0070161,GO:0098793,GO:0098978

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SH3GL1 hsa:6455 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SH3GL1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SH3GL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 SH3GL1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 SH3GL1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TFAP2C SH3GL1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 SH3GL1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SH3GL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 SH3GL1 18668040 22473208 25416803 mrna cleavage,inhibition experimental interaction detection,clip TarBase
URS0000070B1D SH3GL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE SH3GL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 SH3GL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 SH3GL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD SH3GL1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001DE669 SH3GL1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F SH3GL1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 SH3GL1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00006DE17B SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000002103A SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000279B6F SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000015A0D9 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005485E8 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000047A8F SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006372A SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00001919B0 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005CC20C SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000E7139 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000453664 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075B538 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000246356 SH3GL1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SRC SH3GL1 22135298 phosphorylation N/A PhosphoSite
PTK2 SH3GL1 22135298 phosphorylation N/A PhosphoSite
SH3GL1 DNM1 25361965 interaction type N/A PTMCode2
DNM1 SH3GL1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
VPS37C SH3GL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPKOW SH3GL1 21516116 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SGF29 SH3GL1 25348397 N/A physical interaction ComPPI
ANP32B SH3GL1 25348397 N/A physical interaction ComPPI
SH3GLB1 SH3GL1 25348397 N/A physical interaction ComPPI
SH3KBP1 SH3GL1 11894095 24234451 25348397 physical association two hybrid,coimmunoprecipitation,pull down ComPPI,IntAct
GPX7 SH3GL1 25348397 N/A physical interaction ComPPI
VIM SH3GL1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CALM1 SH3GL1 25348397 N/A physical interaction ComPPI
DPPA4 SH3GL1 14525934 16169070 21516116 21900206 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
DPYSL4 SH3GL1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
MAL2 SH3GL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
NF2 SH3GL1 25348397 N/A physical interaction ComPPI
SOCS1 SH3GL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPRO SH3GL1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
KHDRBS1 SH3GL1 25348397 N/A physical interaction ComPPI
GTF2F2 SH3GL1 25348397 N/A physical interaction ComPPI
CREBBP SH3GL1 14525934 15752756 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
PRKACA SH3GL1 25348397 N/A physical interaction ComPPI
ARHGAP1 SH3GL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
YWHAZ SH3GL1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRMT1 SH3GL1 25348397 N/A physical interaction ComPPI
CDH1 SH3GL1 25348397 N/A physical interaction ComPPI
AXIN1 SH3GL1 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
BAG1 SH3GL1 25348397 N/A physical interaction ComPPI
DNM1 SH3GL1 10542231 10764144 14525934 24234451 25348397 9238017 N/A two hybrid,experimental interaction detection,peptide array,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
CALR SH3GL1 25348397 N/A physical interaction ComPPI
RPA1 SH3GL1 25348397 N/A physical interaction ComPPI
EWSR1 SH3GL1 25348397 N/A physical interaction ComPPI
DRD3 SH3GL1 25348397 N/A pull down,physical interaction ComPPI
SPG21 SH3GL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GTF2E1 SH3GL1 25348397 N/A physical interaction ComPPI
FUBP1 SH3GL1 25348397 N/A physical interaction ComPPI
TTC1 SH3GL1 25348397 N/A physical interaction ComPPI
PFDN5 SH3GL1 25348397 N/A physical interaction ComPPI
ITCH SH3GL1 25348397 N/A physical interaction ComPPI
MTA1 SH3GL1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AURKA SH3GL1 25348397 N/A physical interaction ComPPI
TP53RK SH3GL1 25348397 N/A physical interaction ComPPI
SYNJ1 SH3GL1 10542231 10764144 14525934 24234451 25348397 9238017 N/A two hybrid,experimental interaction detection,peptide array,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
ACTR3 SH3GL1 25348397 N/A physical interaction ComPPI
SH3GL3 SH3GL1 14525934 16115810 16169070 21900206 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid pooling approach,in vivo,two hybrid ComPPI,HPRD,IntAct
DNM1L SH3GL1 18330356 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL2 SH3GL1 16115810 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ADRB3 SH3GL1 25348397 N/A pull down,physical interaction ComPPI
RB1CC1 SH3GL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PDCD6IP SH3GL1 12034747 14525934 17350572 21988832 24234451 25348397 colocalization,physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,confocal microscopy,two hybrid ComPPI,HPRD,IntAct
SH3D19 SH3GL1 14525934 14551139 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
PFDN1 SH3GL1 25348397 N/A physical interaction ComPPI
DNM3 SH3GL1 10542231 24234451 25348397 association peptide array ComPPI,IntAct
PML SH3GL1 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
SRGAP3 SH3GL1 24234451 25348397 25819436 physical association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GL1 SH2D4A 14525934 16189514 19060904 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
SH3GL1 ARHGAP8 14525934 15944398 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
SH3GL1 SEPTIN8 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SH3GL1 ITSN2 25348397 N/A physical interaction ComPPI
SH3GL1 LRRK2 22998870 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
SH3GL1 B3GAT1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SH3GL1 AARSD1 25348397 N/A physical interaction ComPPI
SH3GL1 ARPC2 25348397 N/A physical interaction ComPPI
SH3GL1 ACTR2 25348397 N/A physical interaction ComPPI
SH3GL1 ARPC1A 25348397 N/A physical interaction ComPPI
SH3GL1 ARPC4 25348397 N/A physical interaction ComPPI
SH3GL1 ARPC5 25348397 N/A physical interaction ComPPI
SH3GL1 ARPC5L 25348397 N/A physical interaction ComPPI
SH3GL1 CRTAP 25348397 N/A physical interaction ComPPI
SH3GL1 KIFBP 25348397 N/A physical interaction ComPPI
SH3GL1 LAP3 25348397 N/A physical interaction ComPPI
SH3GL1 NIF3L1 25348397 N/A physical interaction ComPPI
SH3GL1 NSUN2 25348397 N/A physical interaction ComPPI
SH3GL1 TRMT10A 25348397 N/A physical interaction ComPPI
SH3GL1 SH3GLB2 25348397 N/A physical interaction ComPPI
SH3GL1 TPRKB 25348397 N/A physical interaction ComPPI
SH3GL1 FAM102A 25348397 N/A physical interaction ComPPI
SH3GL1 AZU1 25348397 N/A physical interaction ComPPI
SH3GL1 POU5F1 25348397 N/A physical interaction ComPPI
SH3GL1 TPTE2 25348397 N/A physical interaction ComPPI
SH3GL1 C8G 25348397 N/A physical interaction ComPPI
SH3GL1 FBXO32 25348397 N/A physical interaction ComPPI
SH3GL1 CHRM4 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 ADRA2A 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 RAPH1 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 ADRA2B 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 CHRM2 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 HRH3 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 HRH1 25348397 N/A pull down,physical interaction ComPPI
SH3GL1 DNM2 10542231 24234451 25348397 association peptide array ComPPI,IntAct
SH3GL1 OTUB1 24234451 25348397 26752685 association anti tag coimmunoprecipitation ComPPI,IntAct
SH3GL1 SCAMP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GL1 CCDC50 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GL1 PRB3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GL1 RHEX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SH3GL1 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
PSMB1 SH3GL1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
THG1L SH3GL1 25348397 N/A physical interaction ComPPI
CALU SH3GL1 25348397 N/A physical interaction ComPPI
SH3GL1 SH3GL1 14525934 16115810 16189514 21900206 24234451 physical association two hybrid,two hybrid array,two hybrid pooling approach,two hybrid prey pooling approach,two hybrid HPRD,IntAct
SRC SH3GL1 16054026 27898060 inhibition N/A OmniPath
PTK2 SH3GL1 16054026 27898060 N/A N/A OmniPath
LRRK2 SH3GL1 22998870 27898060 inhibition N/A OmniPath

Visualization










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