Gene Information gene info

GENE:HCFC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HCFC2
FullNmae host cell factor C2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24972
EnsembleID ENSG00000111727
Uniprot Q9Y5Z7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HCFC2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HCFC2 GO:0000122,GO:0003713,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006338,GO:0006355,GO:0006357,GO:0016032,GO:0016604,GO:0035097,GO:0044665,GO:0045893,GO:0048188,GO:0071339

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HCFC2 hsa:29915 path:hsa03083 Polycomb repressive complex - Homo sapiens (human)
HCFC2 hsa:29915 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IRF2 HCFC2 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 HCFC2 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 HCFC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink

Source Target Pmid Interactiontype Methods Database
URS00003AD231 HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B HCFC2 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 HCFC2 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 HCFC2 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 HCFC2 20371350 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003758F0 HCFC2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 HCFC2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF HCFC2 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000007A060 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 HCFC2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HCFC2 MEN1 25361965 interaction type N/A PTMCode2
MEN1 HCFC2 25361965 interaction type N/A PTMCode2
HCFC2 ASH2L 25361965 interaction type N/A PTMCode2
ASH2L HCFC2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSPA8 HCFC2 25348397 N/A physical interaction ComPPI
NUDCD3 HCFC2 24234451 25036637 25348397 physical association physical interaction,luminescence based mammalian interactome mapping ComPPI,IntAct
HCFC1 HCFC2 25348397 N/A physical interaction ComPPI
ASH2L HCFC2 25348397 N/A molecular sieving,physical interaction ComPPI
MYC HCFC2 21150319 24234451 25348397 association tandem affinity purification ComPPI,IntAct
TUBA4A HCFC2 25348397 N/A physical interaction ComPPI
RBBP5 HCFC2 15199122 24234451 25348397 physical association molecular sieving,physical interaction ComPPI,IntAct
TCP1 HCFC2 25348397 N/A physical interaction ComPPI
CCT5 HCFC2 25348397 N/A physical interaction ComPPI
CCT7 HCFC2 25348397 N/A physical interaction ComPPI
OGT HCFC2 25348397 N/A physical interaction ComPPI
SIRT1 HCFC2 21909281 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
CREB3 HCFC2 25348397 N/A physical interaction ComPPI
NFE2L3 HCFC2 25348397 N/A physical interaction ComPPI
FOXO3 HCFC2 21909281 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
ESR2 HCFC2 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
NUDC HCFC2 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
BAP1 HCFC2 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
IRF2 HCFC2 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KMT2B HCFC2 25348397 N/A physical interaction ComPPI
HELZ HCFC2 25348397 N/A physical interaction ComPPI
CXXC1 HCFC2 25348397 N/A physical interaction ComPPI
KMT2A HCFC2 14525934 15199122 24234451 25348397 association,physical association anti bait coimmunoprecipitation,experimental interaction detection,molecular sieving,physical interaction,in vitro ComPPI,HPRD,IntAct
WDR5 HCFC2 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
DIDO1 HCFC2 25348397 N/A physical interaction ComPPI
CCT4 HCFC2 25348397 N/A physical interaction ComPPI
CCT2 HCFC2 25348397 N/A physical interaction ComPPI
CCT6A HCFC2 25348397 N/A physical interaction ComPPI
KIAA0232 HCFC2 25348397 N/A physical interaction ComPPI
MEN1 HCFC2 15199122 24234451 25348397 physical association molecular sieving,physical interaction ComPPI,IntAct
HCFC2 THAP2 25348397 N/A physical interaction ComPPI
HCFC2 ZNF131 25348397 N/A physical interaction ComPPI
HCFC2 SETD1A 25348397 N/A physical interaction ComPPI
HCFC2 BOD1L1 25348397 N/A physical interaction ComPPI
HCFC2 CCT6B 25348397 N/A physical interaction ComPPI
HCFC2 CCT3 25348397 N/A physical interaction ComPPI
HCFC2 TUBB8 25348397 N/A physical interaction ComPPI
HCFC2 UTP18 15199122 24234451 25348397 physical association molecular sieving ComPPI,IntAct
HCFC2 PPP2R2B 19156129 24234451 25348397 association pull down ComPPI,IntAct

Visualization