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GENE：TK2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TK2
FullNmae thymidine kinase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11831
EnsembleID ENSG00000166548
Uniprot O00142

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TK2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TK2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TK2 GO:0004137,GO:0004797,GO:0005524,GO:0005737,GO:0005739,GO:0005739,GO:0005759,GO:0006139,GO:0009157,GO:0009165,GO:0016310,GO:0019136,GO:0019206,GO:0043097,GO:0046092,GO:0046104,GO:0071897

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TK2 hsa:7084 path:hsa00240 Pyrimidine metabolism - Homo sapiens (human)
TK2 hsa:7084 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)
TK2 hsa:7084 path:hsa01100 Metabolic pathways - Homo sapiens (human)
TK2 hsa:7084 path:hsa01232 Nucleotide metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TK2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TK2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 TK2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 TK2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 TK2 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
DKK1 TK2 25348397 N/A physical interaction ComPPI
CTNNBIP1 TK2 25348397 N/A physical interaction ComPPI
RBM4 TK2 25348397 N/A physical interaction ComPPI

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