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GENE：SETD6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SETD6
FullNmae SET domain containing 6, protein lysine methyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26116
EnsembleID ENSG00000103037
Uniprot Q8TBK2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SETD6 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SETD6 GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005829,GO:0016279,GO:0016279,GO:0016279,GO:0018026,GO:0018026,GO:0019827,GO:0032088,GO:0048863,GO:0050727,GO:0051059,GO:1904047

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SETD6 SETD6 21131967 23180781 methylation reaction methyltransferase radiometric assay InnateDB
RELA SETD6 21131967 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CTCF SETD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SETD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SETD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR SETD6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE SETD6 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 SETD6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00002CF3F0 SETD6 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC SETD6 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATXN1 SETD6 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
RELA SETD6 21131967 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SETD6 SETD6 21131967 24234451 methylation reaction methyltransferase assay IntAct
RELA SETD6 21131967 21515635 27898060 N/A N/A OmniPath
SETD6 RELA 21131967 21515635 27898060 N/A N/A OmniPath

Visualization










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