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GENE：GTF2F1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GTF2F1
FullNmae general transcription factor IIF subunit 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4652
EnsembleID ENSG00000125651
Uniprot P35269

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GTF2F1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GTF2F1 GO:0001091,GO:0001096,GO:0003677,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005669,GO:0005674,GO:0005674,GO:0006366,GO:0006367,GO:0006367,GO:0006368,GO:0009615,GO:0016251,GO:0016251,GO:0019211,GO:0019903,GO:0019904,GO:0030054,GO:0032091,GO:0032968,GO:0032991,GO:0043231,GO:0045944,GO:0045944,GO:1990841

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GTF2F1 hsa:2962 path:hsa03022 Basal transcription factors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GTF2F1 IRF1 15893730 23180781 physical association anti tag coimmunoprecipitation InnateDB
GTF2F1 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 GTF2F1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 GTF2F1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GTF2F1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF GTF2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 GTF2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GTF2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GTF2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GTF2F1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
AR GTF2F1 9238003 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 GTF2F1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000204177 GTF2F1 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 GTF2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 GTF2F1 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000007F792 GTF2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB0E GTF2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000527B00 GTF2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 GTF2F1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D GTF2F1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 GTF2F1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 GTF2F1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC GTF2F1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C GTF2F1 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000047A67D GTF2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 GTF2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD GTF2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C GTF2F1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000605E00 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000044FD7 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000075AB16 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000054A671 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003D5391 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000235862 GTF2F1 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GTF2F1 GTF2F1 22135298 phosphorylation N/A PhosphoSite
GTF2F1 RARG 22135298 phosphorylation N/A PhosphoSite
CDK2 GTF2F1 22135298 phosphorylation N/A PhosphoSite
MSX2 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 MSX2 25361965 interaction type N/A PTMCode2
POLR2J GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 POLR2J 25361965 interaction type N/A PTMCode2
MED21 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 MED21 25361965 interaction type N/A PTMCode2
BRCA1 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 BRCA1 25361965 interaction type N/A PTMCode2
SRF GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 SRF 25361965 interaction type N/A PTMCode2
GTF2B GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 GTF2B 25361965 interaction type N/A PTMCode2
POLR2B GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 POLR2B 25361965 interaction type N/A PTMCode2
AR GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 AR 25361965 interaction type N/A PTMCode2
GTF2E1 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 GTF2E1 25361965 interaction type N/A PTMCode2
POLR2C GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 POLR2C 25361965 interaction type N/A PTMCode2
CTDP1 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 CTDP1 25361965 interaction type N/A PTMCode2
HNRNPU GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 HNRNPU 25361965 interaction type N/A PTMCode2
GTF2E2 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 GTF2E2 25361965 interaction type N/A PTMCode2
CTDSP1 GTF2F1 25361965 interaction type N/A PTMCode2
GTF2F1 CTDSP1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KPNA2 GTF2F1 25348397 N/A physical interaction ComPPI
SF3A3 GTF2F1 25348397 N/A physical interaction ComPPI
CDC73 GTF2F1 25348397 N/A physical interaction ComPPI
SNRPA GTF2F1 25348397 N/A physical interaction ComPPI
ZNRD2 GTF2F1 25348397 N/A physical interaction ComPPI
PSMC3 GTF2F1 25348397 N/A physical interaction ComPPI
C1QTNF2 GTF2F1 25348397 N/A physical interaction ComPPI
COIL GTF2F1 25348397 N/A physical interaction ComPPI
GTF2A1 GTF2F1 11509574 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MED21 GTF2F1 25348397 N/A physical interaction ComPPI
GTF2B GTF2F1 14525934 16878124 24234451 25348397 8662660 N/A experimental interaction detection,pull down,x-ray crystallography,physical interaction,in vitro ComPPI,HPRD,IntAct
TBP GTF2F1 25348397 N/A physical interaction ComPPI
JUN GTF2F1 25348397 N/A physical interaction ComPPI
GTF2F2 GTF2F1 11183778 14525934 24234451 25348397 7854423 8441635 8662660 N/A two hybrid,experimental interaction detection,x-ray crystallography,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
TAF1 GTF2F1 10428810 14525934 24234451 25348397 7590250 8625415 9660973 physical association anti tag coimmunoprecipitation,coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
AR GTF2F1 14525934 20541699 24234451 25348397 9238003 physical association affinity chromatography technology,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
FEZ1 GTF2F1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SRF GTF2F1 14525934 24234451 25348397 27898060 7854423 8106390 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
BCAT1 GTF2F1 25348397 N/A physical interaction ComPPI
GTF2H1 GTF2F1 25348397 N/A physical interaction ComPPI
NTRK1 GTF2F1 25348397 N/A physical interaction ComPPI
PARP1 GTF2F1 25348397 N/A physical interaction ComPPI
PHB GTF2F1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RFC2 GTF2F1 25348397 N/A physical interaction ComPPI
DSCC1 GTF2F1 25348397 N/A physical interaction ComPPI
PSAP GTF2F1 25348397 N/A physical interaction ComPPI
MYC GTF2F1 14525934 25348397 27898060 8755740 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
HNRNPU GTF2F1 25348397 N/A physical interaction ComPPI
CSNK2A1 GTF2F1 25348397 N/A physical interaction ComPPI
FGF9 GTF2F1 25348397 N/A physical interaction ComPPI
THOC5 GTF2F1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
XPO1 GTF2F1 25348397 N/A physical interaction ComPPI
AHR GTF2F1 25348397 N/A physical interaction ComPPI
TAF11 GTF2F1 25348397 N/A physical interaction ComPPI
CTDP1 GTF2F1 12732728 14525934 25348397 9765293 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
SF3A1 GTF2F1 25348397 N/A physical interaction ComPPI
GTF2E2 GTF2F1 11113176 14525934 25348397 9677423 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2E1 GTF2F1 25348397 N/A physical interaction ComPPI
TCEA1 GTF2F1 25348397 N/A physical interaction ComPPI
GTF2H4 GTF2F1 25348397 N/A physical interaction ComPPI
GTF2F1 CTDSP1 12721286 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GTF2F1 MSX2 14525934 25348397 9265625 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GTF2F1 PTN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GTF2F1 MAGEC1 14525934 17137291 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
GTF2F1 PSMC2 11118325 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
GTF2F1 BRCA1 25348397 N/A physical interaction ComPPI
GTF2F1 POLR2A 25348397 N/A physical interaction ComPPI
GTF2F1 ARNT 25348397 N/A physical interaction ComPPI
GTF2F1 FOS 25348397 N/A physical interaction ComPPI
GTF2F1 POLR2B 25348397 N/A physical interaction ComPPI
GTF2F1 MEPCE 25348397 N/A physical interaction ComPPI
GTF2F1 TRIM27 25348397 N/A physical interaction ComPPI
GTF2F1 CDK9 25348397 N/A physical interaction ComPPI
GTF2F1 CCNT1 25348397 N/A physical interaction ComPPI
GTF2F1 ERCC2 24234451 25348397 27193682 physical association physical interaction,electron tomography ComPPI,IntAct
GTF2F1 CDK8 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
GTF2F1 CCNC 25348397 N/A physical interaction ComPPI
GTF2F1 POLR2D 25348397 N/A physical interaction ComPPI
GTF2F1 SRSF9 25348397 N/A physical interaction ComPPI
GTF2F1 CIRBP 25348397 N/A physical interaction ComPPI
GTF2F1 MMS19 25348397 N/A physical interaction ComPPI
GTF2F1 POLR2C 18562274 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F1 DUS3L 25348397 N/A physical interaction ComPPI
GTF2F1 SNF8 25348397 N/A physical interaction ComPPI
GTF2F1 VPS29 25348397 N/A physical interaction ComPPI
GTF2F1 PUS1 25348397 N/A physical interaction ComPPI
GTF2F1 ABL1 25348397 N/A physical interaction ComPPI
GTF2F1 PSME3 25348397 N/A physical interaction ComPPI
GTF2F1 EAF1 25348397 N/A physical interaction ComPPI
GTF2F1 PRPS1 25348397 N/A physical interaction ComPPI
GTF2F1 DEGS1 25348397 N/A physical interaction ComPPI
GTF2F1 PLPPR1 25348397 N/A physical interaction ComPPI
GTF2F1 STAC3 25348397 N/A physical interaction ComPPI
GTF2F1 NCL 25348397 N/A physical interaction ComPPI
GTF2F1 HIRIP3 25348397 N/A physical interaction ComPPI
GTF2F1 MED4 25348397 N/A physical interaction ComPPI
GTF2F1 MED20 25348397 N/A physical interaction ComPPI
GTF2F1 HNRNPA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F1 MYO1C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F1 POLR2F 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F1 POLR2G 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F1 KIF2C 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
GTF2F1 CDC14B 25348397 N/A physical interaction ComPPI
GTF2F1 PHF19 25348397 N/A physical interaction ComPPI
GTF2F1 PIP4K2A 25348397 N/A physical interaction ComPPI
GTF2F1 JMJD6 25348397 N/A physical interaction ComPPI
GTF2F1 PCDH20 25348397 N/A physical interaction ComPPI
GTF2F1 CDK16 25348397 N/A physical interaction ComPPI
GTF2F1 SPRTN 25348397 N/A physical interaction ComPPI
GTF2F1 FGB 25348397 N/A physical interaction ComPPI
GTF2F1 TRIM25 25348397 N/A physical interaction ComPPI
GTF2F1 URI1 12737519 24234451 25348397 physical association anti tag coimmunoprecipitation,far western blotting,pull down ComPPI,IntAct
GTF2F1 CDC37 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GTF2F1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
GTF2F1 POLR2E 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
GTF2F1 DAPK1 24234451 25348397 29513927 N/A protein array ComPPI,IntAct
H3C1 GTF2F1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
POLR2J GTF2F1 25348397 N/A physical interaction ComPPI
EEF1D GTF2F1 25348397 N/A physical interaction ComPPI
SRRM1 GTF2F1 25348397 N/A physical interaction ComPPI
EEF1B2 GTF2F1 25348397 N/A physical interaction ComPPI
SNRNP27 GTF2F1 25348397 N/A physical interaction ComPPI
SPANXA1 GTF2F1 25348397 N/A physical interaction ComPPI
ATF7IP GTF2F1 10777215 14525934 N/A experimental interaction detection HPRD
TFIIFALPHA GTF2F1 24234451 7890767 physical association cosedimentation through density gradient IntAct
H1-2 GTF2F1 24234451 30021884 physical association cross-linking study IntAct
CDK1 GTF2F1 10428810 27898060 N/A N/A OmniPath
GTF2F1 RARG 10748061 27898060 N/A N/A OmniPath

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