GENE：ARHGAP27
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ARHGAP27 |
| FullNmae | Rho GTPase activating protein 27 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:31813 |
| EnsembleID | ENSG00000159314 |
| Uniprot | Q6ZUM4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ARHGAP27 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ARHGAP27 | GO:0005096,GO:0005096,GO:0005737,GO:0005829,GO:0006898,GO:0007165,GO:0016020,GO:0017124,GO:0043087,GO:0043547,GO:0051056 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ARHGAP27 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | ARHGAP27 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | ARHGAP27 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| PRDM14 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | ARHGAP27 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00004214BB | ARHGAP27 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000CC005 | ARHGAP27 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | ARHGAP27 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002373FD | ARHGAP27 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| RAC1 | ARHGAP27 | 25361965 | interaction type | N/A | PTMCode2 |
| ARHGAP27 | RAC1 | 25361965 | interaction type | N/A | PTMCode2 |
| ARHGAP27 | SH3KBP1 | 25361965 | interaction type | N/A | PTMCode2 |
| SH3KBP1 | ARHGAP27 | 25361965 | interaction type | N/A | PTMCode2 |
| CDC42 | ARHGAP27 | 25361965 | interaction type | N/A | PTMCode2 |
| ARHGAP27 | CDC42 | 25361965 | interaction type | N/A | PTMCode2 |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CDC42 | ARHGAP27 | 25348397 | N/A | physical interaction | ComPPI |
| SH3KBP1 | ARHGAP27 | 14525934 15147912 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| RAC1 | ARHGAP27 | 25348397 | N/A | physical interaction | ComPPI |
| ARHGAP27 | TRIM25 | 25348397 | N/A | physical interaction | ComPPI |
| HMGN2 | ARHGAP27 | 24234451 30021884 | physical association | cross-linking study | IntAct |