GENE：UGT2A1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | UGT2A1 |
| FullNmae | UDP glucuronosyltransferase family 2 member A1 complex locus |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:12542 |
| EnsembleID | ENSG00000173610 |
| Uniprot | P0DTE4 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| UGT2A1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| UGT2A1 | GO:0005789,GO:0007606,GO:0007608,GO:0008206,GO:0015020,GO:0015020,GO:0050896,GO:0052695,GO:0052695 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| UGT2A1 | hsa:10941 | path:hsa00040 | Pentose and glucuronate interconversions - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00053 | Ascorbate and aldarate metabolism - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00140 | Steroid hormone biosynthesis - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00830 | Retinol metabolism - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00860 | Porphyrin metabolism - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00980 | Metabolism of xenobiotics by cytochrome P450 - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00982 | Drug metabolism - cytochrome P450 - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa00983 | Drug metabolism - other enzymes - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa01240 | Biosynthesis of cofactors - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa04976 | Bile secretion - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa05204 | Chemical carcinogenesis - DNA adducts - Homo sapiens (human) |
| UGT2A1 | hsa:10941 | path:hsa05207 | Chemical carcinogenesis - receptor activation - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SMARCA4 | UGT2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | UGT2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | UGT2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | UGT2A1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |