GENE：PDE7A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | PDE7A |
| FullNmae | phosphodiesterase 7A |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8791 |
| EnsembleID | ENSG00000205268 |
| Uniprot | Q13946 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| PDE7A | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| PDE7A | GO:0004115,GO:0004115,GO:0005829,GO:0006198,GO:0019933,GO:0019933,GO:0046872 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| PDE7A | hsa:5150 | path:hsa00230 | Purine metabolism - Homo sapiens (human) |
| PDE7A | hsa:5150 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
| PDE7A | hsa:5150 | path:hsa05032 | Morphine addiction - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | PDE7A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | PDE7A | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | PDE7A | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | PDE7A | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | PDE7A | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | PDE7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS2 | PDE7A | 12737631 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| NFKB1 | PDE7A | 12737631 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CREB1 | PDE7A | N/A | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000081E1F | PDE7A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000055128B | PDE7A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004DA9DB | PDE7A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000005D4F5 | PDE7A | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003ACE11 | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001F0C23 | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C5969 | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001FC26E | PDE7A | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000170CF4 | PDE7A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS000035D2F9 | PDE7A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS0000078918 | PDE7A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E008F | PDE7A | 25416803 27292025 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009BB1BF | PDE7A | 27087310 | direct interaction,inhibition | N/A | NPInter |