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GENE：ETF1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ETF1
FullNmae eukaryotic translation termination factor 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3477
EnsembleID ENSG00000120705
Uniprot P62495

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ETF1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ETF1 GO:0000184,GO:0002184,GO:0003723,GO:0003747,GO:0003747,GO:0004045,GO:0005515,GO:0005737,GO:0005737,GO:0005829,GO:0005829,GO:0006415,GO:0006449,GO:0006479,GO:0008079,GO:0008079,GO:0016149,GO:0018444,GO:0018444,GO:0018444,GO:0022626,GO:0043022,GO:1990825,GO:1990825

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ETF1 hsa:2107 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EGR1 ETF1 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB
SMG1 ETF1 19417104 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 ETF1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 ETF1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 ETF1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TP73 ETF1 19558638 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 ETF1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP3 ETF1 14563555 trascriptional regulation,stimulation inferred by curator TFlink
CREB1 ETF1 N/A trascriptional regulation,stimulation inferred by curator TFlink
MYC ETF1 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000BE495 ETF1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000016914 ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000042E1F ETF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ETF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004AF715 ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002F0130 ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C1E1 ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002198F3 ETF1 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027352D ETF1 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000366551 ETF1 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 ETF1 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00002FB065 ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000535FDD ETF1 23446348 23592263 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000027080C ETF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 ETF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 ETF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041E780 ETF1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ETF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ETF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ETF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ETF1 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F ETF1 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000041FA2C ETF1 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RPS7 ETF1 25361965 interaction type N/A PTMCode2
ETF1 RPS7 25361965 interaction type N/A PTMCode2
ABCE1 ETF1 25361965 interaction type N/A PTMCode2
ETF1 ABCE1 25361965 interaction type N/A PTMCode2
PABPC1 ETF1 25361965 interaction type N/A PTMCode2
ETF1 PABPC1 25361965 interaction type N/A PTMCode2
KEAP1 ETF1 25361965 interaction type N/A PTMCode2
ETF1 KEAP1 25361965 interaction type N/A PTMCode2
RPL36 ETF1 25361965 interaction type N/A PTMCode2
ETF1 RPL36 25361965 interaction type N/A PTMCode2
EEF1B2 ETF1 25361965 interaction type N/A PTMCode2
ETF1 EEF1B2 25361965 interaction type N/A PTMCode2
GSPT1 ETF1 25361965 interaction type N/A PTMCode2
ETF1 GSPT1 25361965 interaction type N/A PTMCode2
ETF1 EIF2S2 25361965 interaction type N/A PTMCode2
EIF2S2 ETF1 25361965 interaction type N/A PTMCode2
ETF1 PPP2CA 25361965 interaction type N/A PTMCode2
PPP2CA ETF1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 ETF1 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDC5L ETF1 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
RPS7 ETF1 25348397 N/A physical interaction ComPPI
CEP43 ETF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SGTB ETF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRAF6 ETF1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
KEAP1 ETF1 14525934 16189514 19615732 24234451 25348397 25416956 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
RBM8A ETF1 19417104 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
JUN ETF1 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
LIG4 ETF1 25348397 N/A physical interaction ComPPI
KPNB1 ETF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
DLD ETF1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
BAG6 ETF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PSMA1 ETF1 25348397 N/A physical interaction ComPPI
EIF2S1 ETF1 25348397 N/A physical interaction ComPPI
PPP2CA ETF1 14525934 25348397 27898060 9003791 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,OmniPath
PABPC1 ETF1 25348397 N/A physical interaction ComPPI
XPO1 ETF1 25348397 N/A physical interaction ComPPI
SMG1 ETF1 16452507 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
ABCE1 ETF1 25348397 N/A physical interaction ComPPI
PDCD4 ETF1 25348397 N/A physical interaction ComPPI
GEMIN5 ETF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CYP1A1 ETF1 25348397 N/A physical interaction ComPPI
EGFR ETF1 25348397 N/A physical interaction ComPPI
GTF2E2 ETF1 25348397 N/A physical interaction ComPPI
ACTL6A ETF1 25348397 N/A physical interaction ComPPI
PSMD2 ETF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
VCAM1 ETF1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
FGB ETF1 25348397 N/A physical interaction ComPPI
UPF1 ETF1 18256688 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ETF1 GSPT2 14525934 18447585 24234451 25348397 9712840 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct
ETF1 GSPT1 18256688 24234451 25348397 27898060 9712840 9928949 association,physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
ETF1 ALB 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ETF1 HECW2 25348397 N/A physical interaction ComPPI
ETF1 CORO1B 25348397 N/A physical interaction ComPPI
ETF1 CORO1C 25348397 N/A physical interaction ComPPI
ETF1 NUDC 25348397 N/A physical interaction ComPPI
ETF1 RTF1 25348397 N/A physical interaction ComPPI
ETF1 VPS26A 25348397 N/A physical interaction ComPPI
ETF1 TSN 25348397 N/A physical interaction ComPPI
ETF1 MBD5 25348397 N/A physical interaction ComPPI
ETF1 FSD1 25348397 N/A physical interaction ComPPI
ETF1 RNF26 25348397 N/A physical interaction ComPPI
ETF1 EIF2S2 25348397 N/A physical interaction ComPPI
ETF1 BZW1 25348397 N/A physical interaction ComPPI
ETF1 DNAJB1 25348397 N/A physical interaction ComPPI
ETF1 DNAJB4 25348397 N/A physical interaction ComPPI
ETF1 HYOU1 25348397 N/A physical interaction ComPPI
ETF1 LARS1 25348397 N/A physical interaction ComPPI
ETF1 NCKAP1 25348397 N/A physical interaction ComPPI
ETF1 SYAP1 25348397 N/A physical interaction ComPPI
ETF1 ZPR1 25348397 N/A physical interaction ComPPI
ETF1 USP47 25348397 N/A physical interaction ComPPI
ETF1 MRPS11 25348397 N/A physical interaction ComPPI
ETF1 SLC38A7 25348397 N/A physical interaction ComPPI
ETF1 G3BP1 25348397 N/A physical interaction ComPPI
ETF1 CCND2 25348397 N/A physical interaction ComPPI
ETF1 CSNK1A1 12062430 24234451 25348397 physical association imaging technique ComPPI,IntAct
ETF1 IKBKE 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ETF1 TRMT10C 18984158 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
ETF1 MLF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
ETF1 BCAR1 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
ETF1 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
FKBPL ETF1 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
SNRNP27 ETF1 25348397 N/A physical interaction ComPPI
RAB34 ETF1 24234451 30021884 physical association cross-linking study IntAct

Visualization










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