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GENE：SLC12A4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SLC12A4
FullNmae solute carrier family 12 member 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10913
EnsembleID ENSG00000124067
Uniprot Q9UP95

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SLC12A4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SLC12A4 GO:0005515,GO:0005524,GO:0005765,GO:0005886,GO:0005886,GO:0005886,GO:0006811,GO:0006884,GO:0007268,GO:0008519,GO:0015379,GO:0015379,GO:0015379,GO:0015379,GO:0016020,GO:0019901,GO:0045202,GO:0055064,GO:0055064,GO:0055075,GO:0055075,GO:0071805,GO:0140157,GO:1902476,GO:1990573

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 SLC12A4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C SLC12A4 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 SLC12A4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000065D58 SLC12A4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection,experimental interaction detection TarBase
URS0000338542 SLC12A4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00000C85B2 SLC12A4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 SLC12A4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
STK39 SLC12A4 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
LGALS3 SLC12A4 25348397 N/A physical interaction ComPPI
KRTAP12-2 SLC12A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LGALS9C SLC12A4 25348397 N/A physical interaction ComPPI
AP3M1 SLC12A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LYN SLC12A4 25348397 N/A physical interaction ComPPI
PTH1R SLC12A4 25348397 N/A physical interaction ComPPI
CHRND SLC12A4 25348397 N/A physical interaction ComPPI
LGALS8 SLC12A4 25348397 N/A physical interaction ComPPI
PLP2 SLC12A4 25348397 N/A physical interaction ComPPI
TRIM25 SLC12A4 25348397 N/A physical interaction ComPPI
TNFRSF10A SLC12A4 25348397 N/A physical interaction ComPPI
TGOLN2 SLC12A4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 SLC12A4 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FLOT1 SLC12A4 25348397 N/A physical interaction ComPPI
TMEM102 SLC12A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ILF3 SLC12A4 25348397 N/A physical interaction ComPPI
HSD17B10 SLC12A4 25348397 N/A physical interaction ComPPI
ZNF655 SLC12A4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM189A2 SLC12A4 25348397 N/A physical interaction ComPPI
CD55 SLC12A4 25348397 N/A physical interaction ComPPI
TMEM43 SLC12A4 25348397 N/A physical interaction ComPPI
TMEM216 SLC12A4 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
MTNR1B SLC12A4 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
SLC12A4 LGALS9 25348397 N/A physical interaction ComPPI
SLC12A4 LYPD6 25348397 N/A physical interaction ComPPI
SLC12A4 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SLC12A4 PPM1H 25348397 N/A physical interaction ComPPI
SLC12A4 NRN1 25348397 N/A physical interaction ComPPI
SLC12A4 IL17RC 25348397 N/A physical interaction ComPPI
SLC12A4 SLC17A2 25348397 N/A physical interaction ComPPI
SLC12A4 GPR21 25348397 N/A physical interaction ComPPI
SLC12A4 PCDHA3 25348397 N/A physical interaction ComPPI
SLC12A4 PCDHB16 25348397 N/A physical interaction ComPPI
SLC12A4 FAM189B 25348397 N/A physical interaction ComPPI
SLC12A4 ATF7IP 14525934 15231748 24234451 25348397 physical association two hybrid,two hybrid ComPPI,HPRD,IntAct
SLC12A4 CYSRT1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC12A4 CNFN 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC12A4 MB21D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC12A4 KRTAP19-2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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