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GENE：FCER1G

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FCER1G
FullNmae Fc epsilon receptor Ig
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3611
EnsembleID ENSG00000158869
Uniprot P30273

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FCER1G immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FCER1G GO:0002283,GO:0002292,GO:0002431,GO:0005515,GO:0005886,GO:0005886,GO:0009897,GO:0009986,GO:0010543,GO:0016064,GO:0019767,GO:0019863,GO:0019864,GO:0019886,GO:0030593,GO:0031623,GO:0032753,GO:0032998,GO:0033001,GO:0038094,GO:0038095,GO:0038156,GO:0042590,GO:0042742,GO:0042802,GO:0042803,GO:0045087,GO:0050766,GO:0070821,GO:0071404,GO:0101003

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FCER1G hsa:2207 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
FCER1G hsa:2207 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
FCER1G hsa:2207 path:hsa04611 Platelet activation - Homo sapiens (human)
FCER1G hsa:2207 path:hsa04625 C-type lectin receptor signaling pathway - Homo sapiens (human)
FCER1G hsa:2207 path:hsa04650 Natural killer cell mediated cytotoxicity - Homo sapiens (human)
FCER1G hsa:2207 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
FCER1G hsa:2207 path:hsa05152 Tuberculosis - Homo sapiens (human)
FCER1G hsa:2207 path:hsa05310 Asthma - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CD247 FCER1G 10358164 10562324 10925299 11353765 11385609 11438547 11449354 11489965 11513144 11875494 11994457 12055234 12393695 12731048 12811837 15081523 15099567 15778339 16287995 16713974 17100877 18768831 20435894 20814939 21059766 2139103 22267813 23414611 23508573 24378531 24445665 26192618 7523143 8344348 8478617 8551221 9603467 9625766 9738502 9751747 interaction type N/A ACSN
FCER1G FCAR 12731048 15081523 15099567 20814939 23414611 2451784 26192618 7590867 9625766 9952373 interaction type N/A ACSN
FCER1G HLA-G 10562324 10925299 11353765 11385609 11438547 11489965 11513144 11875494 11994457 12055234 12731048 12811837 15081523 15778339 16287995 16713974 17100877 20435894 20814939 21059766 22267813 23414611 23508573 24378531 26192618 8478617 9603467 9625766 9738502 9751747 interaction type N/A ACSN
FCER1G KIR2DL4 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
FCER1G SYK 12731048 15081523 15099567 20814939 23414611 2451784 26192618 7590867 9625766 9952373 interaction type N/A ACSN
FCER1G ZAP70 10358164 10562324 10925299 11353765 11438547 11449354 11875494 12393695 12415267 12731048 12811837 15081523 15099567 15735648 16713974 17371980 18768831 20435894 20814939 21059766 2139103 23414611 23508573 23620508 23886063 24378531 24445665 26192618 7523143 7600293 8344348 8478617 8551221 8642247 9603467 9625766 9738502 interaction type N/A ACSN
FYN FCER1G 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 26192618 27192565 9738502 interaction type N/A ACSN
LCK FCER1G 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 26192618 8478617 8986721 9438848 9738502 9751747 interaction type N/A ACSN
CLEC2D FCER1G 16339513 18159636 20435894 22378844 24227772 26192618 8478617 9603467 interaction type N/A ACSN
KLRB1 FCER1G 16339513 18159636 20435894 22378844 24227772 26192618 8478617 9603467 interaction type N/A ACSN
HLA-E FCER1G 10358164 11015446 11062502 12731048 15120186 15536084 22464172 26192618 2731048 8478617 9485206 9486650 9655483 interaction type N/A ACSN
KLRD1 FCER1G 10358164 11015446 11062502 12731048 15120186 15536084 22464172 26192618 2731048 8478617 9485206 9486650 9655483 interaction type N/A ACSN
HCK FCER1G 12524384 21910624 24445665 26192618 8064233 8132624 8478617 interaction type N/A ACSN
LYN FCER1G 12524384 19909365 21910624 24445665 26192618 26552706 8064233 8132624 8478617 8892616 interaction type N/A ACSN
FCER1G SHC1 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 26192618 7523143 8344348 8478617 8551221 9603467 9625766 9738502 interaction type N/A ACSN
FCER1G CD48 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
FCER1G SH2D1A 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
FCER1G PTPN11 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
CRP FCER1G 11801683 15531769 26192618 3489521 interaction type N/A ACSN
FCER1G TNF 12731048 15081523 15099567 20814939 23414611 2451784 26192618 7590867 9625766 9952373 interaction type N/A ACSN
FCER1G TBX21 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 26192618 7523143 8344348 8478617 8551221 9603467 9625766 9738502 interaction type N/A ACSN
FCER1G IFNG 10925299 11438547 11489965 11513144 11875494 11994457 12055234 12811837 15081523 15778339 16287995 16713974 17100877 20435894 23414611 23508573 24378531 26192618 9625766 9751747 interaction type N/A ACSN
FCER1G IL6 12731048 15081523 15099567 20814939 23414611 2451784 26192618 7590867 9625766 9952373 interaction type N/A ACSN
PLCG2 FCER1G 10469124 23180781 physical association anti tag coimmunoprecipitation InnateDB
SYK FCER1G 23180781 8663460 physical association anti tag coimmunoprecipitation,gst pull down InnateDB
KIR2DL4 FCER1G 15778339 18292514 23180781 physical association anti tag coimmunoprecipitation InnateDB
FCER1A FCER1G 15845448 23180781 physical association anti tag coimmunoprecipitation InnateDB
NCR1 FCER1G 15778339 23180781 physical association anti tag coimmunoprecipitation InnateDB
SP1 FCER1G 18378679 23180781 physical association electrophoretic mobility supershift assay InnateDB
ELF1 FCER1G 18378679 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
GABPA FCER1G 18378679 23180781 physical association anti tag coimmunoprecipitation,electrophoretic mobility supershift assay InnateDB
GABPB1 FCER1G 18378679 23180781 physical association electrophoretic mobility supershift assay InnateDB

Source Target Pmid Interactiontype Methods Database
YBX1 FCER1G 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA FCER1G 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FCER1G 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRKCD FCER1G 22135298 phosphorylation N/A PhosphoSite
PRKACA FCER1G 22135298 phosphorylation N/A PhosphoSite
PRKCB FCER1G 22135298 phosphorylation N/A PhosphoSite
FCER1G BTK 25361965 interaction type N/A PTMCode2
BTK FCER1G 25361965 interaction type N/A PTMCode2
FCER1G GP6 25361965 interaction type N/A PTMCode2
GP6 FCER1G 25361965 interaction type N/A PTMCode2
FCER1G FCER1A 25361965 interaction type N/A PTMCode2
FCER1A FCER1G 25361965 interaction type N/A PTMCode2
FCER1G FCGR3A 25361965 interaction type N/A PTMCode2
FCGR3A FCER1G 25361965 interaction type N/A PTMCode2
FCER1G SYK 25361965 interaction type N/A PTMCode2
SYK FCER1G 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
LMNA FCER1G 25348397 N/A physical interaction ComPPI
BTK FCER1G 11788586 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SYK FCER1G 14525934 24234451 25348397 8071371 8810294 9280292 association,physical association experimental interaction detection,pull down,physical interaction,kinase scintillation proximity assay,in vitro,in vivo ComPPI,HPRD,IntAct
GP6 FCER1G 10825177 24234451 25348397 27898060 9280292 physical association anti bait coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct,OmniPath
LYN FCER1G 11388899 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
FCGR3A FCER1G 25348397 N/A in vivo ComPPI
PLCG2 FCER1G 25348397 N/A in vivo ComPPI
NCR1 FCER1G 10049942 24234451 25348397 physical association anti bait coimmunoprecipitation,in vivo ComPPI,IntAct
FCAR FCER1G 25348397 N/A physical interaction ComPPI
FCER1A FCER1G 14525934 25348397 8752908 N/A experimental interaction detection,in vivo ComPPI,HPRD
FCER1G KIR2DL4 14525934 15778339 18292514 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
FCER1G CLEC4C 17850179 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct

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