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GENE：IMPA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IMPA2
FullNmae inositol monophosphatase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6051
EnsembleID ENSG00000141401
Uniprot O14732

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IMPA2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IMPA2 GO:0005515,GO:0005737,GO:0005829,GO:0006020,GO:0006021,GO:0006796,GO:0007165,GO:0008934,GO:0008934,GO:0010226,GO:0042803,GO:0046854,GO:0046872,GO:0052832,GO:0052833

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IMPA2 hsa:3613 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
IMPA2 hsa:3613 path:hsa01100 Metabolic pathways - Homo sapiens (human)
IMPA2 hsa:3613 path:hsa04070 Phosphatidylinositol signaling system - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR IMPA2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA2 IMPA2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
MYC IMPA2 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 IMPA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TFAP2A IMPA2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE IMPA2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000475586 IMPA2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000331800 IMPA2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0920 IMPA2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CARHSP1 IMPA2 25348397 N/A physical interaction ComPPI
CYCS IMPA2 25348397 N/A physical interaction ComPPI
ARHGDIA IMPA2 25348397 N/A physical interaction ComPPI
DUT IMPA2 25348397 N/A physical interaction ComPPI
PABPC4 IMPA2 25348397 N/A physical interaction ComPPI
TXN IMPA2 25348397 N/A physical interaction ComPPI
HNRNPL IMPA2 25348397 N/A physical interaction ComPPI
FSCN1 IMPA2 25348397 N/A physical interaction ComPPI
RDX IMPA2 25348397 N/A physical interaction ComPPI
MSN IMPA2 25348397 N/A physical interaction ComPPI
NPPA IMPA2 25348397 N/A physical interaction ComPPI
PLIN3 IMPA2 25348397 N/A physical interaction ComPPI
PDCD6 IMPA2 25348397 N/A physical interaction ComPPI
ALDOC IMPA2 25348397 N/A physical interaction ComPPI
TRIM25 IMPA2 25348397 N/A physical interaction ComPPI
STMN1 IMPA2 25348397 N/A physical interaction ComPPI
TNFRSF14 IMPA2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PARK7 IMPA2 25348397 N/A physical interaction ComPPI
IMPA1 IMPA2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBA3 IMPA2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ADSS2 IMPA2 25348397 N/A physical interaction ComPPI
HERPUD1 IMPA2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PGLS IMPA2 25348397 N/A physical interaction ComPPI
PAICS IMPA2 25348397 N/A physical interaction ComPPI
ALDOA IMPA2 25348397 N/A physical interaction ComPPI
CCT6A IMPA2 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
IMPA2 GLO1 25348397 N/A physical interaction ComPPI

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