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GENE：KDSR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KDSR
FullNmae 3-ketodihydrosphingosine reductase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4021
EnsembleID ENSG00000119537
Uniprot Q06136

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KDSR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KDSR GO:0005515,GO:0005615,GO:0005783,GO:0005789,GO:0005789,GO:0006666,GO:0006666,GO:0016020,GO:0030148,GO:0030148,GO:0047560,GO:0047560,GO:0047560,GO:0047560

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
KDSR hsa:2531 path:hsa00600 Sphingolipid metabolism - Homo sapiens (human)
KDSR hsa:2531 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
KDSR EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR KDSR 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 KDSR 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 KDSR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 KDSR 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 KDSR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000ED600 KDSR 20215506 25416803 mrna cleavage,inhibition array technology TarBase
URS00000BE495 KDSR 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000016914 KDSR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 KDSR 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 KDSR 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 KDSR 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000030F801 KDSR 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 KDSR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000AA464 KDSR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000367985 KDSR 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 KDSR 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000183BED KDSR 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000011DF KDSR 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003AD2AA KDSR 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000600E6 KDSR 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000475586 KDSR 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RPN1 KDSR 25348397 N/A physical interaction ComPPI
VCP KDSR 25348397 N/A physical interaction ComPPI
CANX KDSR 25348397 N/A physical interaction ComPPI
MAPK6 KDSR 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAB1A KDSR 25348397 N/A physical interaction ComPPI
EPRS1 KDSR 25348397 N/A physical interaction ComPPI
SSR4 KDSR 25348397 N/A physical interaction ComPPI
RAB1B KDSR 25348397 N/A physical interaction ComPPI
ELAVL1 KDSR 25348397 N/A physical interaction ComPPI
CLGN KDSR 25348397 N/A physical interaction ComPPI
TSPAN3 KDSR 25348397 N/A physical interaction ComPPI
POMK KDSR 25348397 N/A physical interaction ComPPI
RPN2 KDSR 25348397 N/A physical interaction ComPPI
RELL1 KDSR 25348397 N/A physical interaction ComPPI
TSPAN17 KDSR 25348397 N/A physical interaction ComPPI
RAB1C KDSR 25348397 N/A physical interaction ComPPI
ACADSB KDSR 25348397 N/A physical interaction ComPPI
RDH13 KDSR 25348397 N/A physical interaction ComPPI
REEP5 KDSR 25348397 N/A physical interaction ComPPI
KDSR IPPK 25348397 N/A physical interaction ComPPI

Visualization










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