GENE:NUDT5
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NUDT5 |
| FullNmae | nudix hydrolase 5 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:8052 |
| EnsembleID | ENSG00000165609 |
| Uniprot | Q9UKK9 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NUDT5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NUDT5 | GO:0000287,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005829,GO:0006338,GO:0006753,GO:0009117,GO:0009191,GO:0016779,GO:0019144,GO:0019303,GO:0019303,GO:0019693,GO:0030515,GO:0042802,GO:0042803,GO:0044715,GO:0044716,GO:0047631,GO:0047631,GO:0047631,GO:0055086,GO:0070062,GO:1990966 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| NUDT5 | hsa:11164 | path:hsa00230 | Purine metabolism - Homo sapiens (human) |
| NUDT5 | hsa:11164 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | NUDT5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA1 | NUDT5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | NUDT5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ETS1 | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000070B1D | NUDT5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00000EED18 | NUDT5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000277201 | NUDT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000057A7C | NUDT5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000353492 | NUDT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000435A77 | NUDT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | NUDT5 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | NUDT5 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000047944F | NUDT5 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | NUDT5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000224AEA | NUDT5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| COX5B | NUDT5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TRAF6 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| H2BC4 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| PPP1R12A | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| SLC9A3R2 | NUDT5 | 24234451 25348397 27173435 | association,physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
| NTRK1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| GORASP2 | NUDT5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| MAPK6 | NUDT5 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| EIF6 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| EWSR1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| RPA2 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| CUL1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| DUSP14 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| YAP1 | NUDT5 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| CTNNB1 | NUDT5 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| SMURF1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
| MAD2L1 | NUDT5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| PRKAB1 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| IKBKE | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| HSPB9 | NUDT5 | 15503857 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
| MCC | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SKA1 | NUDT5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| NUDT5 | PYCR1 | 25348397 | N/A | physical interaction | ComPPI |
| NUDT5 | PYCR2 | 25348397 | N/A | physical interaction | ComPPI |
| NUDT5 | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
| NUDT5 | HLA-B | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| GH1 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
