GENE:NUDT5
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | NUDT5 |
FullNmae | nudix hydrolase 5 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:8052 |
EnsembleID | ENSG00000165609 |
Uniprot | Q9UKK9 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
NUDT5 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
NUDT5 | GO:0000287,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005829,GO:0006338,GO:0006753,GO:0009117,GO:0009191,GO:0016779,GO:0019144,GO:0019303,GO:0019303,GO:0019693,GO:0030515,GO:0042802,GO:0042803,GO:0044715,GO:0044716,GO:0047631,GO:0047631,GO:0047631,GO:0055086,GO:0070062,GO:1990966 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
NUDT5 | hsa:11164 | path:hsa00230 | Purine metabolism - Homo sapiens (human) |
NUDT5 | hsa:11164 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | NUDT5 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
GATA1 | NUDT5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | NUDT5 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F1 | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ETS1 | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | NUDT5 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000070B1D | NUDT5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000EED18 | NUDT5 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000277201 | NUDT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000057A7C | NUDT5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000353492 | NUDT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000435A77 | NUDT5 | 22012620 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000075BDA4 | NUDT5 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000004BACE | NUDT5 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000047944F | NUDT5 | 19536157 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00000011DF | NUDT5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000224AEA | NUDT5 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
COX5B | NUDT5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TRAF6 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
H2BC4 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
PPP1R12A | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
SLC9A3R2 | NUDT5 | 24234451 25348397 27173435 | association,physical association | physical interaction,tandem affinity purification,inference by socio-affinity scoring | ComPPI,IntAct |
NTRK1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
CDH1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
GORASP2 | NUDT5 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
MAPK6 | NUDT5 | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
EIF6 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
EWSR1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
RPA2 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
CUL1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
DUSP14 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
YAP1 | NUDT5 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
CTNNB1 | NUDT5 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
SMURF1 | NUDT5 | 25348397 | N/A | physical interaction | ComPPI |
MAD2L1 | NUDT5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
PRKAB1 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
IKBKE | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
HSPB9 | NUDT5 | 15503857 24234451 25348397 | physical association | two hybrid | ComPPI,IntAct |
MCC | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
SKA1 | NUDT5 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
NUDT5 | PYCR1 | 25348397 | N/A | physical interaction | ComPPI |
NUDT5 | PYCR2 | 25348397 | N/A | physical interaction | ComPPI |
NUDT5 | H2BC11 | 25348397 | N/A | physical interaction | ComPPI |
NUDT5 | HLA-B | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
GH1 | NUDT5 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |