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GENE：LAS1L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LAS1L
FullNmae LAS1 like ribosome biogenesis factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25726
EnsembleID ENSG00000001497
Uniprot Q9Y4W2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LAS1L immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LAS1L GO:0000460,GO:0000470,GO:0003723,GO:0004519,GO:0005515,GO:0005654,GO:0005730,GO:0016020,GO:0030687,GO:0071339,GO:0090730

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 LAS1L 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 LAS1L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LAS1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LAS1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 LAS1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LAS1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 LAS1L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002075FA LAS1L 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDC5L LAS1L 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BMI1 LAS1L 25348397 N/A physical interaction ComPPI
AIM2 LAS1L 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL10 LAS1L 25348397 N/A physical interaction ComPPI
PPP1R15A LAS1L 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
PNKP LAS1L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CUL3 LAS1L 25348397 N/A physical interaction ComPPI
UBC LAS1L 25348397 N/A physical interaction ComPPI
NTRK1 LAS1L 25348397 N/A physical interaction ComPPI
PELP1 LAS1L 21326211 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
MYC LAS1L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
DUSP16 LAS1L 24234451 25348397 28330616 association pull down ComPPI,IntAct
ECT2 LAS1L 25348397 N/A physical interaction ComPPI
XPO1 LAS1L 25348397 N/A physical interaction ComPPI
RPS6 LAS1L 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SUMO2 LAS1L 25348397 N/A physical interaction ComPPI
SOX2 LAS1L 25348397 N/A physical interaction ComPPI
RAF1 LAS1L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RNF2 LAS1L 25348397 N/A physical interaction ComPPI
CDK7 LAS1L 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
MDC1 LAS1L 25348397 N/A physical interaction ComPPI
CDK8 LAS1L 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CUL7 LAS1L 25348397 N/A physical interaction ComPPI
CAND1 LAS1L 25348397 N/A physical interaction ComPPI
FOXA1 LAS1L 25348397 N/A physical interaction ComPPI
BARD1 LAS1L 25348397 N/A physical interaction ComPPI
ESR2 LAS1L 21182203 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient ComPPI,IntAct
AURKAIP1 LAS1L 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
SENP3 LAS1L 21326211 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
NES LAS1L 25348397 N/A physical interaction ComPPI
CEP250 LAS1L 25348397 N/A physical interaction ComPPI
IFI16 LAS1L 25348397 N/A physical interaction ComPPI
AGO1 LAS1L 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RRP1B LAS1L 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
TSC22D1 LAS1L 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
L3MBTL1 LAS1L 24234451 25348397 27705803 association tandem affinity purification ComPPI,IntAct
ETS1 LAS1L 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
WDR5 LAS1L 15960975 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FBL LAS1L 24234451 25348397 29568061 association pull down,proximity-dependent biotin identification ComPPI,IntAct
MNDA LAS1L 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
SIRT7 LAS1L 25348397 N/A physical interaction ComPPI
WDR18 LAS1L 25348397 N/A physical interaction ComPPI
TEX10 LAS1L 25348397 N/A physical interaction ComPPI
FOS LAS1L 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
PASK LAS1L 25348397 N/A physical interaction ComPPI
LAS1L SMARCAD1 25348397 N/A physical interaction ComPPI
LAS1L CBX6 21282530 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
LAS1L IPO5 25348397 N/A physical interaction ComPPI
LAS1L OBSL1 25348397 N/A physical interaction ComPPI
LAS1L ZNF746 25348397 N/A physical interaction ComPPI
LAS1L LRRK2 24234451 24725412 25348397 association tandem affinity purification ComPPI,IntAct
LAS1L PYHIN1 24234451 25348397 25665578 association anti tag coimmunoprecipitation ComPPI,IntAct
NOL9 LAS1L 25348397 N/A physical interaction ComPPI
LAS1L RPGRIP1L 24234451 30021884 physical association cross-linking study IntAct

Visualization










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