GENE：ABCD4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ABCD4 |
| FullNmae | ATP binding cassette subfamily D member 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:68 |
| EnsembleID | ENSG00000119688 |
| Uniprot | O14678 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ABCD4 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ABCD4 | GO:0005324,GO:0005515,GO:0005524,GO:0005524,GO:0005765,GO:0005765,GO:0005777,GO:0005778,GO:0005789,GO:0006635,GO:0007031,GO:0009235,GO:0009235,GO:0015420,GO:0015420,GO:0015420,GO:0015889,GO:0015889,GO:0015910,GO:0016020,GO:0016887,GO:0042626,GO:0042626,GO:0042760,GO:0042802,GO:0043190,GO:0055085,GO:1990830 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| ABCD4 | hsa:5826 | path:hsa02010 | ABC transporters - Homo sapiens (human) |
| ABCD4 | hsa:5826 | path:hsa04146 | Peroxisome - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | ABCD4 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ABCD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ABCD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | ABCD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ABCD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ABCD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ABCD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| PDGFRB | ABCD4 | 25348397 | N/A | physical interaction | ComPPI |
| KCNA5 | ABCD4 | 25348397 | N/A | physical interaction | ComPPI |
| XRCC6 | ABCD4 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| PEA15 | ABCD4 | 14525934 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid | ComPPI,HPRD,IntAct |
| ATP2B2 | ABCD4 | 25348397 | N/A | physical interaction | ComPPI |
| FSHR | ABCD4 | 25348397 | N/A | physical interaction | ComPPI |
| TNFRSF10A | ABCD4 | 25348397 | N/A | physical interaction | ComPPI |
| ABCD4 | HSPB2 | 24234451 25348397 26465331 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| ABCD4 | FAM189B | 25348397 | N/A | physical interaction | ComPPI |
| ATP5F1B | ABCD4 | 24234451 30021884 | physical association | cross-linking study | IntAct |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000481F31 | ABCD4 | 27087310 | direct interaction,inhibition | N/A | NPInter |