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GENE：CYP46A1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CYP46A1
FullNmae cytochrome P450 family 46 subfamily A member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2641
EnsembleID ENSG00000036530
Uniprot Q9Y6A2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CYP46A1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CYP46A1 GO:0005506,GO:0005783,GO:0005789,GO:0006699,GO:0006707,GO:0006707,GO:0006707,GO:0006707,GO:0006805,GO:0007399,GO:0008395,GO:0016125,GO:0020037,GO:0020037,GO:0030425,GO:0033781,GO:0033781,GO:0033781,GO:0042448,GO:0062184,GO:0098793,GO:0098794,GO:1900271,GO:1903044

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CYP46A1 hsa:10858 path:hsa00120 Primary bile acid biosynthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 CYP46A1 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 CYP46A1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CYP46A1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP3 CYP46A1 20930312 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000078918 CYP46A1 25416803 28735896 mrna cleavage,inhibition clip TarBase
URS00002B7450 CYP46A1 25416803 28735896 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CLK1 CYP46A1 25348397 N/A physical interaction ComPPI
RIN3 CYP46A1 24234451 25348397 25814554 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct

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