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GENE：LNX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol LNX2
FullNmae ligand of numb-protein X 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20421
EnsembleID ENSG00000139517
Uniprot Q8N448

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
LNX2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
LNX2 GO:0004842,GO:0005515,GO:0005886,GO:0030165,GO:0030182,GO:0042802,GO:0046872,GO:0061351

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 LNX2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF LNX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 LNX2 20584899 rna interference,inhibition experimental interaction detection miRSponge
URS0000338542 LNX2 20584899 25416803 mrna cleavage,inhibition experimental interaction detection,experimental interaction detection TarBase
URS000019F055 LNX2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS0000610EFA LNX2 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A LNX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000137EDE LNX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003FBC84 LNX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000006372A LNX2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000355E82 LNX2 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LNX2 NUMB 25361965 interaction type N/A PTMCode2
NUMB LNX2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
ZNF581 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
TCL1A LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
UBE2I LNX2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RBM17 LNX2 25348397 N/A physical interaction ComPPI
YJU2 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
MAPK9 LNX2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
FHL3 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
PPIL1 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
TBC1D7 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
GLRX3 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
ATP5F1B LNX2 25348397 N/A physical interaction ComPPI
CDKN2C LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
TUBB LNX2 25348397 N/A physical interaction ComPPI
MRFAP1L1 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
OPTN LNX2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CRK LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
NUDT14 LNX2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 NUMB 11782429 11922143 14525934 25348397 25814554 26451611 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
LNX2 LNX1 11922143 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
LNX2 UBE2Z 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LNX2 UBE2T 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LNX2 CD8A 25348397 N/A physical interaction ComPPI
LNX2 PRKCA 25348397 N/A physical interaction ComPPI
LNX2 PLEKHG5 25348397 N/A physical interaction ComPPI
LNX2 CXADR 15979067 25348397 27898060 N/A physical interaction ComPPI,OmniPath
LNX2 PKDREJ 25348397 N/A physical interaction ComPPI
LNX2 PDZRN3 25348397 N/A physical interaction ComPPI
LNX2 PDZRN4 25348397 N/A physical interaction ComPPI
LNX2 CBX4 25348397 N/A physical interaction ComPPI
LNX2 SHISA2 25348397 N/A physical interaction ComPPI
LNX2 USP2 25348397 N/A physical interaction ComPPI
LNX2 RLIM 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LNX2 RNF138 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
LNX2 LATS2 25348397 N/A physical interaction ComPPI
LNX2 IGSF5 25348397 N/A physical interaction ComPPI
LNX2 NXF1 25348397 N/A physical interaction ComPPI
LNX2 PEG10 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 MSRB3 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 MYLIP 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 IL16 25348397 N/A physical interaction ComPPI
LNX2 NMD3 25348397 N/A physical interaction ComPPI
LNX2 IP6K2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 SCLY 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 PTCD3 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 MAP2K5 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 TRAF2 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 VTN 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 PAAT 25348397 N/A physical interaction ComPPI
LNX2 LRRC8E 25348397 N/A physical interaction ComPPI
LNX2 PHYKPL 25348397 N/A physical interaction ComPPI
LNX2 PIK3R3 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LNX2 SRSF11 25348397 N/A physical interaction ComPPI
LNX2 UBE2D2 25348397 N/A physical interaction ComPPI
LNX2 TRIM25 25348397 N/A physical interaction ComPPI
LNX2 NOTCH1 25348397 N/A physical interaction ComPPI
LNX2 SMARCB1 25348397 N/A physical interaction ComPPI
LNX2 EPHA7 25348397 N/A physical interaction ComPPI
LNX2 SYNGAP1 25348397 N/A physical interaction ComPPI
LNX2 KLHL11 25348397 N/A physical interaction ComPPI
LNX2 E4F1 21666599 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
LNX2 PSMF1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 EAF2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 POLR1C 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 GRAP2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 TAB1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 L3MBTL2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 CDK4 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 DRAP1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 UBE2H 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 TRAF1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 SCNM1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 NTAQ1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 RPA2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 CCT3 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 GRB2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 PSMD5 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 FANCG 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 ROPN1 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 PPIH 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 TIFA 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 GADD45A 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 INMT 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 CDK2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 PARVG 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 SH3GLB2 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 LGALS14 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
LNX2 RAB6B 24234451 25348397 27107012 physical association validated two hybrid,barcode fusion genetics two hybrid ComPPI,IntAct
DDA1 LNX2 25348397 N/A physical interaction ComPPI
LNX2 LNX2 24234451 25416956 physical association two hybrid array IntAct
IKBKG LNX2 24234451 30561431 association virotrap IntAct

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