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GENE：PHACTR3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHACTR3
FullNmae phosphatase and actin regulator 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15833
EnsembleID ENSG00000087495
Uniprot Q96KR7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHACTR3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PHACTR3 GO:0003779,GO:0004864,GO:0005515,GO:0005654,GO:0016363,GO:0030036

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
LYL1 PHACTR3 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GATA2 PHACTR3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 PHACTR3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PHACTR3 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PHACTR3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CDK5 PHACTR3 22135298 phosphorylation N/A PhosphoSite
PPP1CA PHACTR3 25361965 interaction type N/A PTMCode2
PHACTR3 PPP1CA 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PPP1CC PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
LXN PHACTR3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACTB PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1CB PHACTR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MCM2 PHACTR3 25348397 N/A physical interaction ComPPI
GTF2I PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
PPP1CA PHACTR3 12925532 14525934 15231748 22321011 24234451 25348397 27898060 28330616 association,physical association two hybrid,experimental interaction detection,pull down,physical interaction,in vivo,two hybrid ComPPI,HPRD,IntAct,OmniPath
MAPK6 PHACTR3 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LRPPRC PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
H3-3A PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
ILF2 PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
AMH PHACTR3 24234451 25348397 28330616 physical association pull down ComPPI,IntAct
KCNK3 PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
EIF3A PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
EIF3B PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
EIF3L PHACTR3 24234451 25348397 28330616 association pull down ComPPI,IntAct
EEF1G PHACTR3 14525934 16169070 25348397 N/A two hybrid,physical interaction,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD
CAPNS2 PHACTR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBL5 PHACTR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHACTR3 TAB1 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PHACTR3 CYB5B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHACTR3 UBIAD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHACTR3 PLPP6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHACTR3 RRP12 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 GALNT9 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 SLIRP 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 NSUN2 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 RPL36A 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 ILF3 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 CAPRIN1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 G3BP1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 ATP10B 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 CPVL 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 LSM14A 24234451 25348397 28330616 association pull down ComPPI,IntAct
PHACTR3 ACTC1 24234451 25348397 28330616 association pull down ComPPI,IntAct
EVI5L PHACTR3 26186194 30476227 physical association affinity chromatography technology TheBiogrid
NOSTRIN PHACTR3 28514442 30476227 physical association affinity chromatography technology TheBiogrid
CDK5 PHACTR3 21487013 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B54D2 PHACTR3 27087310 direct interaction,inhibition N/A NPInter

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