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GENE：PIK3R5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PIK3R5
FullNmae phosphoinositide-3-kinase regulatory subunit 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30035
EnsembleID ENSG00000141506
Uniprot Q8WYR1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PIK3R5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PIK3R5 apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PIK3R5 GO:0005634,GO:0005737,GO:0005829,GO:0005829,GO:0005886,GO:0005942,GO:0005943,GO:0005944,GO:0006955,GO:0007186,GO:0007186,GO:0007186,GO:0016020,GO:0031683,GO:0034451,GO:0043406,GO:0043406,GO:0043491,GO:0046935,GO:0051897

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PIK3R5 hsa:23533 path:hsa04022 cGMP-PKG signaling pathway - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04151 PI3K-Akt signaling pathway - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04371 Apelin signaling pathway - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04611 Platelet activation - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04725 Cholinergic synapse - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa05145 Toxoplasmosis - Homo sapiens (human)
PIK3R5 hsa:23533 path:hsa05167 Kaposi sarcoma-associated herpesvirus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PIK3R5 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PIK3R5 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PIK3R5 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PIK3R5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F2 PIK3R5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TTR PIK3R5 18624398 24234451 25348397 physical association two hybrid ComPPI,IntAct
PIK3CG PIK3R5 10488142 12507995 14525934 24234451 25241761 25348397 physical association experimental interaction detection,physical interaction,in vivo,proximity ligation assay ComPPI,HPRD,IntAct
PIK3R5 SDHB 18624398 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PIK3R5 APP 25348397 N/A physical interaction ComPPI
PIK3R5 CXCL2 18624398 24234451 25348397 physical association two hybrid ComPPI,IntAct

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