GENE:RAB21
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RAB21 |
| FullNmae | RAB21, member RAS oncogene family |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:18263 |
| EnsembleID | ENSG00000080371 |
| Uniprot | Q9UL25 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RAB21 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RAB21 | GO:0000139,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005525,GO:0005768,GO:0005769,GO:0005789,GO:0005802,GO:0005829,GO:0005925,GO:0006886,GO:0008089,GO:0008089,GO:0009898,GO:0012505,GO:0012506,GO:0017157,GO:0019003,GO:0030516,GO:0031901,GO:0032154,GO:0032482,GO:0032580,GO:0045202,GO:0048260,GO:0050775,GO:0050821,GO:0070062,GO:0098559,GO:1904115,GO:2000643 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| E2F4 | RAB21 | 17531812 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | RAB21 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | RAB21 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | RAB21 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | RAB21 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000171CD1 | RAB21 | 18362358 | rna interference,inhibition | quantitative reverse transcription pcr | miRSponge |
| URS0000171CD1 | RAB21 | 18362358 25416803 | mrna cleavage,inhibition | quantitative reverse transcription pcr | TarBase |
| URS0000065D58 | RAB21 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS0000070B1D | RAB21 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000029979D | RAB21 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000012A1DD | RAB21 | 24447584 24477653 25416803 | mrna cleavage,inhibition | western blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay | TarBase |
| URS000006FDD4 | RAB21 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000285DCB | RAB21 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000204177 | RAB21 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077AED | RAB21 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000017DBB8 | RAB21 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BA274 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004B4B85 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000011DF | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000224AEA | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D2F5 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004E008F | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002FF522 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB14 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000AB32B | RAB21 | 19536157 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A6D0C | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000029D9F1 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075BDA4 | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000022AAA | RAB21 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | RAB21 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | RAB21 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | RAB21 | 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| MCM2 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| APPL1 | RAB21 | 17581628 24234451 25348397 | N/A | pull down,physical interaction | ComPPI,IntAct |
| ITGB1 | RAB21 | 16754960 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| GBA | RAB21 | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| LAMTOR3 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| RABGEF1 | RAB21 | 25348397 | N/A | x-ray crystallography,physical interaction,physical interaction | ComPPI |
| GDI1 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| TUBA1A | RAB21 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| ATXN3 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| FANCE | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| CUL7 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| VIPR2 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| HNRNPF | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| SOD1 | RAB21 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| TGOLN2 | RAB21 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| MACF1 | RAB21 | 22705394 24234451 25348397 | physical association | anti tag coimmunoprecipitation,two hybrid fragment pooling approach | ComPPI,IntAct |
| IKBKE | RAB21 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| P2RX1 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| RAB2B | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| MCC | RAB21 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| KSR1 | RAB21 | 24234451 25348397 27086506 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| VAC14 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| KCTD7 | RAB21 | 25348397 | N/A | physical interaction | ComPPI |
| HLA-B | RAB21 | 17353931 24234451 25348397 | physical association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| SDHA | RAB21 | 24234451 25348397 29128334 | association | cross-linking study,physical interaction | ComPPI,IntAct |
| RAB21 | VSIG2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB21 | SLC22A16 | 25348397 | N/A | physical interaction | ComPPI |
| RAB21 | DPAGT1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB21 | RUSF1 | 25348397 | N/A | physical interaction | ComPPI |
| RAB21 | FUCA2 | 25348397 | N/A | physical interaction | ComPPI |
| RAB21 | HCCS | 24234451 25348397 | physical association | physical interaction,inference by socio-affinity scoring | ComPPI,IntAct |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009B3388 | RAB21 | 27087310 | direct interaction,inhibition | N/A | NPInter |
