Gene Information gene info

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GENE：RNF216

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RNF216
FullNmae ring finger protein 216
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21698
EnsembleID ENSG00000011275
Uniprot Q9NWF9

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RNF216 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RNF216 GO:0005515,GO:0005634,GO:0005654,GO:0005829,GO:0005829,GO:0006915,GO:0008270,GO:0032480,GO:0032648,GO:0043161,GO:0050691,GO:0061630,GO:0070936

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF216 TLR4 15107846 23180781 physical association two hybrid InnateDB
RNF216 TIRAP 16968706 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF216 TRAF3 19893624 23180781 physical association anti tag coimmunoprecipitation InnateDB
RNF216 TLR9 15107846 23180781 physical association two hybrid InnateDB
RNF216 KIR2DL4 21270397 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB
RNF216 IRF8 22096565 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR RNF216 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 RNF216 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RNF216 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 RNF216 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 RNF216 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 RNF216 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000AD002 RNF216 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD RNF216 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AF715 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00007455B8 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 RNF216 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003ACE11 RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005651EE RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002D349B RNF216 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA RNF216 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 RNF216 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UBE2L3 RNF216 25361965 interaction type N/A PTMCode2
RNF216 UBE2L3 25361965 interaction type N/A PTMCode2
RIPK1 RNF216 25361965 interaction type N/A PTMCode2
RNF216 RIPK1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBASH3A RNF216 25348397 N/A two hybrid ComPPI
UBASH3B RNF216 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TNFAIP3 RNF216 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
OPTN RNF216 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2L3 RNF216 14525934 15107846 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct
TIRAP RNF216 25348397 N/A physical interaction ComPPI
TRAF3 RNF216 25348397 N/A physical interaction ComPPI
UBAC1 RNF216 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
XPO1 RNF216 25348397 N/A physical interaction ComPPI
TLR4 RNF216 14525934 15107846 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RIPK1 RNF216 11854271 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
UBE2D3 RNF216 25348397 N/A physical interaction ComPPI
BECN1 RNF216 25348397 N/A physical interaction ComPPI
TRIM25 RNF216 25348397 N/A physical interaction ComPPI
UBE2L6 RNF216 14525934 15107846 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,two hybrid prey pooling approach ComPPI,HPRD,IntAct
AGFG1 RNF216 11854271 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RNF216 TLR3 14525934 15107846 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RNF216 TLR5 14525934 15107846 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RNF216 TLR9 14525934 15107846 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
RNF216 UBE2H 25348397 N/A physical interaction ComPPI
RNF216 UBE2C 25348397 N/A physical interaction ComPPI
RNF216 TICAM1 25348397 N/A physical interaction ComPPI
RNF216 KIR2DL2 25348397 N/A physical interaction ComPPI
RNF216 KIR3DS1 25348397 N/A physical interaction ComPPI
RNF216 KIR2DL5A 25348397 N/A physical interaction ComPPI
RNF216 KIR2DL4 21270397 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RNF216 BRCA1 25348397 N/A physical interaction ComPPI
RNF216 RNF11 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RNF216 MOV10 25348397 N/A physical interaction ComPPI
RNF216 NXF1 25348397 N/A physical interaction ComPPI
RNF216 ARC 25348397 N/A physical interaction ComPPI
RNF216 CAPN15 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF216 MORC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF216 YOD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF216 ZFAND2A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF216 RNF216 14525934 16169070 N/A two hybrid HPRD
TLR4 RNF216 15107846 27898060 N/A N/A OmniPath
RNF216 TLR9 15107846 27898060 N/A N/A OmniPath
TIRAP RNF216 16968706 27898060 N/A N/A OmniPath
RNF216 TIRAP 16968706 27898060 N/A N/A OmniPath
TRAF3 RNF216 19893624 27898060 N/A N/A OmniPath

Visualization










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