Gene Information gene info

  1. Home

GENE：TPMT

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TPMT
FullNmae thiopurine S-methyltransferase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12014
EnsembleID ENSG00000137364
Uniprot P51580

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TPMT immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TPMT GO:0005515,GO:0005829,GO:0006139,GO:0006805,GO:0006805,GO:0008119,GO:0008119,GO:0008119,GO:0032259,GO:0042178,GO:1904047

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
TPMT hsa:7172 path:hsa00983 Drug metabolism - other enzymes - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RELA TPMT 12208876 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR TPMT 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 TPMT 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SP1 TPMT 20350137 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SP3 TPMT 20350137 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
FOXP3 TPMT 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
HNF4A TPMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 TPMT 18971253 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 TPMT 20350137 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004AF715 TPMT 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000016FD1A TPMT 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000003ABC4 TPMT 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075AB14 TPMT 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C1E1 TPMT 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
APP TPMT 25348397 N/A physical interaction ComPPI

Visualization










  Return