GENE:EHD4
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | EHD4 |
| FullNmae | EH domain containing 4 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:3245 |
| EnsembleID | ENSG00000103966 |
| Uniprot | Q9H223 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| EHD4 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| EHD4 | GO:0003676,GO:0005509,GO:0005515,GO:0005524,GO:0005525,GO:0005634,GO:0005737,GO:0005769,GO:0005783,GO:0005886,GO:0006897,GO:0006907,GO:0016020,GO:0030100,GO:0030139,GO:0031901,GO:0032456,GO:0032456,GO:0045296,GO:0048471,GO:0050731,GO:0051260,GO:0055038,GO:0055038,GO:0060271,GO:0070062,GO:0071363,GO:0072659 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| EHD4 | hsa:30844 | path:hsa04144 | Endocytosis - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | EHD4 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | EHD4 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | EHD4 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | EHD4 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| FOXP3 | EHD4 | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | EHD4 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000324096 | EHD4 | 18668040 25416803 | mrna cleavage,inhibition | experimental interaction detection | TarBase |
| URS000016D2D4 | EHD4 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000008B558 | EHD4 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000049FAE8 | EHD4 | 22291592 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000568FF8 | EHD4 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F859B | EHD4 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00005D986D | EHD4 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000508C13 | EHD4 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D814 | EHD4 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000075CC78 | EHD4 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00001012BC | EHD4 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000004BACE | EHD4 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000047944F | EHD4 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021202F | EHD4 | 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| SNW1 | EHD4 | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CDC5L | EHD4 | 20467437 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MCM2 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| EXOC8 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| TGFBR2 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| NTRK1 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| CDH1 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| PPP1CA | EHD4 | 24234451 25348397 25593058 | association | anti bait coimmunoprecipitation | ComPPI,IntAct |
| PTPRM | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| MICALL1 | EHD4 | 19864458 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| RBSN | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| CLTC | EHD4 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| UBA2 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| EGFR | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| UQCRC2 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| NOL3 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| TNFRSF13B | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| H2AC4 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| GTF3C4 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| MTMR2 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| DDX19B | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM11 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| EHD1 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| WARS1 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| ANK2 | EHD4 | 20489164 24234451 25348397 | physical association | pull down | ComPPI,IntAct |
| CTPS2 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| AFP | EHD4 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RPL38 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| PLCG1 | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| DDOST | EHD4 | 25348397 | N/A | physical interaction | ComPPI |
| EHD4 | RASGRF1 | 21988832 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| EHD4 | ADSL | 25348397 | N/A | physical interaction | ComPPI |
| EHD4 | ZC3HC1 | 25348397 | N/A | physical interaction | ComPPI |
| EHD4 | TPCN2 | 25348397 | N/A | physical interaction | ComPPI |
| EHD4 | NTRK3 | 25348397 | N/A | physical interaction | ComPPI |
