Gene Information gene info

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GENE：GABRB1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GABRB1
FullNmae gamma-aminobutyric acid type A receptor subunit beta1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4081
EnsembleID ENSG00000163288
Uniprot P18505

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GABRB1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GABRB1 GO:0004890,GO:0004890,GO:0005254,GO:0005635,GO:0005886,GO:0005886,GO:0005886,GO:0006811,GO:0007165,GO:0007165,GO:0007214,GO:0007268,GO:0009636,GO:0015276,GO:0021954,GO:0022851,GO:0022851,GO:0030425,GO:0030594,GO:0032570,GO:0034707,GO:0042391,GO:0042698,GO:0043005,GO:0045202,GO:0048787,GO:0050811,GO:0050877,GO:0060078,GO:0071420,GO:0098685,GO:0098982,GO:0099505,GO:0099507,GO:0099507,GO:0099507,GO:0099634,GO:0150047,GO:1902476,GO:1902476,GO:1902711,GO:1902711,GO:1902711,GO:1904315

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GABRB1 hsa:2560 path:hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human)
GABRB1 hsa:2560 path:hsa04723 Retrograde endocannabinoid signaling - Homo sapiens (human)
GABRB1 hsa:2560 path:hsa04726 Serotonergic synapse - Homo sapiens (human)
GABRB1 hsa:2560 path:hsa04727 GABAergic synapse - Homo sapiens (human)
GABRB1 hsa:2560 path:hsa05032 Morphine addiction - Homo sapiens (human)
GABRB1 hsa:2560 path:hsa05033 Nicotine addiction - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR GABRB1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GABRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GABRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GABRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 GABRB1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004DA9DB GABRB1 19536157 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 GABRB1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5BAA GABRB1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D GABRB1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001A405B GABRB1 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000209F04 GABRB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003B59DF GABRB1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000000EF0B GABRB1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB GABRB1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 GABRB1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 GABRB1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 GABRB1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 GABRB1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000246356 GABRB1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001D4A78 GABRB1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CC379 GABRB1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000016FF9C GABRB1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000008F0CF GABRB1 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000075AB16 GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000605E00 GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000015D23B GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C0D3F GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004407DC GABRB1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 GABRB1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000006B702 GABRB1 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 GABRB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000366551 GABRB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000027352D GABRB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001481F9 GABRB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002198F3 GABRB1 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000041FA2C GABRB1 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 GABRB1 25348397 N/A physical interaction ComPPI
PIK3CA GABRB1 11606067 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
GABRB1 C1QBP 11350968 14525934 25348397 27898060 N/A two hybrid,two hybrid ComPPI,HPRD,OmniPath
GABRB1 UBQLN1 25348397 N/A physical interaction ComPPI
GABRB1 CUL1 25348397 N/A physical interaction ComPPI
GABRB1 NOD1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GABRB1 FKBP5 24234451 25036637 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GABRB1 AKAP5 12595241 14525934 N/A experimental interaction detection HPRD
ARFGEF2 GABRB1 14525934 15198677 N/A two hybrid HPRD
PRKCA GABRB1 1321150 27898060 N/A N/A OmniPath

Visualization










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