Gene Information gene info

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GENE：ACTN3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ACTN3
FullNmae actinin alpha 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:165
EnsembleID ENSG00000248746
Uniprot Q08043

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ACTN3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ACTN3 GO:0005178,GO:0005509,GO:0005515,GO:0005829,GO:0005884,GO:0005886,GO:0005903,GO:0005925,GO:0008307,GO:0014728,GO:0014732,GO:0014883,GO:0014894,GO:0030018,GO:0030036,GO:0030054,GO:0030864,GO:0031143,GO:0031448,GO:0042802,GO:0042981,GO:0042995,GO:0044325,GO:0045820,GO:0048041,GO:0048633,GO:0048743,GO:0051015,GO:0055001,GO:0060349,GO:0070062,GO:0070885,GO:0090324,GO:0120163,GO:1900159,GO:1901078,GO:1903715,GO:1904025

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ACTN3 hsa:89 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ACTN3 ACTN4 23180781 25416956 physical association two hybrid InnateDB
ACTN3 ACTN1 23180781 25416956 physical association two hybrid InnateDB
REL ACTN3 23180781 25416956 physical association two hybrid InnateDB
TRAF1 ACTN3 23180781 25416956 physical association two hybrid InnateDB
TRAF2 ACTN3 23180781 25416956 physical association two hybrid InnateDB
ACTN3 NEBL 23180781 25416956 physical association two hybrid InnateDB
ACTN3 ABI3 23180781 25416956 physical association two hybrid InnateDB
ACTN3 RNF111 23180781 25416956 physical association two hybrid InnateDB
ACTN3 PLEKHG2 23180781 25416956 physical association two hybrid InnateDB
ACTN3 C1ORF94 23180781 25416956 physical association two hybrid InnateDB
ACTN3 KCTD6 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
SMARCA4 ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ACTN3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
RTP5 ACTN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT6C ACTN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FAM90A1 ACTN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 KCTD6 25348397 N/A two hybrid,physical interaction ComPPI
ACTN3 ACTN2 10656685 25348397 27898060 9675099 N/A physical interaction,in vitro,in vivo ComPPI,OmniPath
ACTN3 NRAP 25348397 N/A two hybrid,in vitro ComPPI
ACTN3 MYPN 25348397 N/A two hybrid,physical interaction ComPPI
ACTN3 ACTN4 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,in vivo,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ADORA2A 25348397 N/A two hybrid,in vitro ComPPI
ACTN3 ACTN1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 REL 25348397 N/A physical interaction ComPPI
ACTN3 TRAF1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 TRAF2 25348397 N/A physical interaction ComPPI
ACTN3 NEBL 25348397 N/A physical interaction ComPPI
ACTN3 ABI3 25348397 N/A physical interaction ComPPI
ACTN3 RNF111 25348397 N/A physical interaction ComPPI
ACTN3 PLEKHG2 25348397 N/A physical interaction ComPPI
ACTN3 C1ORF94 25348397 N/A physical interaction ComPPI
ACTN3 BRCA1 25348397 N/A physical interaction ComPPI
ACTN3 PDLIM1 25348397 N/A physical interaction ComPPI
ACTN3 MYH15 25348397 N/A physical interaction ComPPI
ACTN3 MYH7 25348397 N/A physical interaction ComPPI
ACTN3 AKAP17A 25348397 N/A physical interaction ComPPI
ACTN3 LRRCC1 25348397 N/A physical interaction ComPPI
ACTN3 BCHE 25348397 N/A physical interaction ComPPI
ACTN3 CFTR 25348397 N/A physical interaction ComPPI
ACTN3 YWHAZ 20618440 24234451 25348397 association tandem affinity purification ComPPI,IntAct
ACTN3 ESR2 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
ACTN3 FBP1 12507293 24234451 25348397 physical association biochemical ComPPI,IntAct
ACTN3 TTN 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ACTN3 DUX1 24234451 25348397 26816005 physical association two hybrid ComPPI,IntAct
ACTN3 DUX4L9 24234451 25348397 26816005 physical association two hybrid ComPPI,IntAct
ACTN3 SCRIB 24234451 24550280 25348397 physical association phage display ComPPI,IntAct
ACTN3 CXCL5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 IVD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 CTDSP1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ATP23 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 DDAH2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 NDUFAB1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ASB9 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ZNF343 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 MAGEA6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 CTAG1A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 PPP1R18 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 MYOZ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 LNX1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 TRIM29 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 MYOT 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 USP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 SNAI1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 C2CD6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 PCCB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 MICALL2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 NKAPD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 PTK6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 GLIS2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ODF3B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 C20ORF85 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 SOHLH1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ECM1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 LINC01565 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 POU6F2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 UBE2DNL 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 DDIT4L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ZNF426 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 HGS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ACTN3 ACTN3 24234451 physical association two hybrid array,two hybrid prey pooling approach IntAct
PTK2 ACTN3 11369769 15070900 27898060 inhibition N/A OmniPath
SH3KBP1 ACTN3 15070900 27898060 inhibition N/A OmniPath

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