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GENE：CHD2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CHD2
FullNmae chromodomain helicase DNA binding protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1917
EnsembleID ENSG00000173575
Uniprot O14647

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CHD2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CHD2 GO:0000785,GO:0000978,GO:0003677,GO:0003682,GO:0003723,GO:0004386,GO:0005515,GO:0005524,GO:0005634,GO:0005634,GO:0006357,GO:0006974,GO:0007517,GO:0010467,GO:0016887,GO:0034728,GO:0042393,GO:0042393,GO:0060218,GO:0140658

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR CHD2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 CHD2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 CHD2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 CHD2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
TP73 CHD2 21245298 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
FOXP3 CHD2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 CHD2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 CHD2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000052E1A6 CHD2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 CHD2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TEKT1 CHD2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SUMO1 CHD2 17000644 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
PHB CHD2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
HNRNPL CHD2 25348397 N/A physical interaction ComPPI
UHRF2 CHD2 25348397 N/A physical interaction ComPPI
CTR9 CHD2 25348397 N/A physical interaction ComPPI
EED CHD2 25348397 N/A physical interaction ComPPI
MID2 CHD2 25348397 N/A physical interaction ComPPI
SRPK2 CHD2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
PARK7 CHD2 20127688 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
LNX1 CHD2 25348397 N/A physical interaction ComPPI
THAP1 CHD2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
BEND7 CHD2 25348397 N/A physical interaction ComPPI
TRIM41 CHD2 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIRT7 CHD2 25348397 N/A physical interaction ComPPI
LEO1 CHD2 25348397 N/A physical interaction ComPPI
PAF1 CHD2 25348397 N/A physical interaction ComPPI
CHD2 TULP3 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
SMC1A CHD2 24234451 30021884 physical association cross-linking study IntAct
FLNA CHD2 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS000075A1CF CHD2 27087310 direct interaction,inhibition N/A NPInter

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