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GENE：GIT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GIT2
FullNmae GIT ArfGAP 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4273
EnsembleID ENSG00000139436
Uniprot Q14161

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GIT2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GIT2 GO:0005096,GO:0005515,GO:0005654,GO:0005925,GO:0007420,GO:0008277,GO:0031267,GO:0032012,GO:0036465,GO:0045202,GO:0046872,GO:0098793

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GIT2 hsa:9815 path:hsa04144 Endocytosis - Homo sapiens (human)
GIT2 hsa:9815 path:hsa05135 Yersinia infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IKBKG GIT2 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
GIT2 TRAF1 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
GIT2 TSN 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB
GIT2 TNIP1 21988832 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR GIT2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 GIT2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 GIT2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 GIT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000006FDD4 GIT2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000055128B GIT2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 GIT2 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 GIT2 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATM GIT2 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
NCK2 GIT2 25348397 N/A physical interaction ComPPI
KRT18 GIT2 21988832 24234451 25348397 colocalization,physical association two hybrid,physical interaction,confocal microscopy ComPPI,IntAct
CORO1A GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
OIP5 GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TFPT GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PAK2 GIT2 17353931 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TNFAIP3 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ACTG1 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RABGGTB GIT2 25348397 N/A physical interaction ComPPI
QPRT GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
YWHAG GIT2 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TNIP1 GIT2 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PAK1 GIT2 16628223 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction,in vitro,in vivo ComPPI,IntAct
SMAD3 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAFF GIT2 25348397 N/A physical interaction ComPPI
MVP GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ACTN1 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT1 GIT2 12473661 14525934 16628223 24234451 25348397 physical association anti bait coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
PXN GIT2 16628223 22728435 24234451 25348397 physical association anti bait coimmunoprecipitation,pull down,physical interaction,in vitro,in vivo ComPPI,IntAct
HMG20A GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
C4BPA GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GOLGA5 GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RABEP1 GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RABGEF1 GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
RUFY1 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
EXOC1 GIT2 25348397 N/A physical interaction ComPPI
RCVRN GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
E2F2 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TRAF1 GIT2 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
NFKBIB GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GRK2 GIT2 10896954 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
TGFB1I1 GIT2 10330411 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
LMNB1 GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
NCKIPSD GIT2 25348397 N/A physical interaction ComPPI
LPXN GIT2 25348397 N/A physical interaction ComPPI
GUSB GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PAK3 GIT2 10896954 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ARHGEF6 GIT2 25348397 N/A physical interaction ComPPI
ARHGEF7 GIT2 10428811 10896954 14525934 16628223 24234451 25348397 physical association anti bait coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
GIT2 PCLO 25348397 N/A physical interaction ComPPI
GIT2 TSN 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 IKBKG 21988832 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction,two hybrid array ComPPI,IntAct
GIT2 SH3GLB2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 GCH1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 NME2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 PROX1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 SPOP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 SAFB2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 RUSC2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 CALCOCO2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 HNRNPUL1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 ATF5 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 EDC4 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 UBQLN1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 KCTD5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 USHBP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
GIT2 POLR1B 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
GIT2 MOV10 25348397 N/A physical interaction ComPPI
GIT2 MED4 25348397 N/A physical interaction ComPPI
GIT2 FBXO28 25348397 N/A physical interaction ComPPI
GIT2 SYNC 25348397 N/A physical interaction ComPPI
GIT2 ICAM1 25348397 N/A physical interaction ComPPI
GIT2 KLHL2 25348397 N/A physical interaction ComPPI
GIT2 CAMK4 25348397 N/A physical interaction ComPPI
GIT2 TMOD4 25348397 N/A physical interaction ComPPI
GIT2 PKN3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 NCKAP5L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 CCHCR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 YEATS4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 TUFT1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 RABGAP1L 25348397 N/A physical interaction ComPPI
GIT2 RABGAP1L 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 CLOCK 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 PSMD9 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 VPS53 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 DZIP3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 GRIPAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 RCOR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 VPS50 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 CCDC93 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 PHF21A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 CAVIN1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 PHLDB3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 HAUS6 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 RPRD1A 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 KCTD7 25348397 N/A physical interaction ComPPI
GIT2 ARNTL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 MAX 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 NUF2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 VPS51 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 EIPR1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
GIT2 LAMTOR5 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
ASS1 GIT2 25348397 N/A physical interaction ComPPI
THAP11 GIT2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
HGD GIT2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ATM GIT2 25605334 27898060 N/A N/A OmniPath
GIT2 IKBKG 21988832 27898060 N/A N/A OmniPath
PTPN12 GIT2 16317044 27898060 inhibition N/A OmniPath

Visualization










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