GENE：MYO7A
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | MYO7A |
| FullNmae | myosin VIIA |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:7606 |
| EnsembleID | ENSG00000137474 |
| Uniprot | Q13402 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| MYO7A | lysosomal_cd | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| MYO7A | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| MYO7A | GO:0000146,GO:0000146,GO:0001750,GO:0001845,GO:0001917,GO:0005515,GO:0005516,GO:0005524,GO:0005737,GO:0005737,GO:0005765,GO:0005829,GO:0005902,GO:0005938,GO:0006886,GO:0007015,GO:0007040,GO:0007423,GO:0007601,GO:0007605,GO:0007605,GO:0008104,GO:0015629,GO:0016324,GO:0019904,GO:0030048,GO:0030050,GO:0030507,GO:0031477,GO:0031982,GO:0032391,GO:0032420,GO:0042462,GO:0042470,GO:0042490,GO:0042802,GO:0043531,GO:0045202,GO:0048563,GO:0050953,GO:0050957,GO:0051015,GO:0051015,GO:0051904,GO:0060088,GO:0120044,GO:1990435 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| MYO7A | hsa:4647 | path:hsa04814 | Motor proteins - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | MYO7A | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | MYO7A | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP73 | MYO7A | 19558638 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| CEBPA | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | MYO7A | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| CALM1 | MYO7A | 25348397 | N/A | physical interaction | ComPPI |
| KEAP1 | MYO7A | 11921171 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| KHDRBS1 | MYO7A | 25348397 | N/A | physical interaction | ComPPI |
| PRKAR1A | MYO7A | 10889203 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| CDH1 | MYO7A | 25348397 | N/A | physical interaction | ComPPI |
| MAP2 | MYO7A | 25348397 | N/A | physical interaction,in vivo | ComPPI |
| MYO7A | USH1C | 12485990 12588794 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vitro,in vivo | ComPPI,HPRD |
| MYO7A | VEZT | 11080149 14525934 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| MYO7A | MYRIP | 11964381 12221080 14525934 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| MYO7A | ACTA1 | 12466270 14525934 18160714 25348397 27898060 | N/A | experimental interaction detection,in vitro | ComPPI,HPRD,OmniPath |
| MYO7A | CTNNA1 | 25348397 | N/A | physical interaction | ComPPI |
| MYO7A | CTNNB1 | 25348397 | N/A | physical interaction | ComPPI |
| MYO7A | MGMT | 25348397 | N/A | physical interaction | ComPPI |
| MYO7A | CALM2 | 11171103 14525934 | N/A | experimental interaction detection | HPRD |
| STK38L | MYO7A | 24234451 30108113 | association | proximity-dependent biotin identification | IntAct |