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GENE：GPX7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol GPX7
FullNmae glutathione peroxidase 7
LocusType gene with protein product
Status Approved
HGNC_id HGNC:4559
EnsembleID ENSG00000116157
Uniprot Q96SL4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
GPX7 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
GPX7 GO:0004096,GO:0004601,GO:0004601,GO:0004602,GO:0005515,GO:0005576,GO:0005783,GO:0005788,GO:0034599,GO:0098869

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
GPX7 hsa:2882 path:hsa00480 Glutathione metabolism - Homo sapiens (human)
GPX7 hsa:2882 path:hsa01100 Metabolic pathways - Homo sapiens (human)
GPX7 hsa:2882 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)
GPX7 hsa:2882 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
GPX7 hsa:2882 path:hsa05016 Huntington disease - Homo sapiens (human)
GPX7 hsa:2882 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GET3 GPX7 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
GATA1 GPX7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 GPX7 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 GPX7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 GPX7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA GPX7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 GPX7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 GPX7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS GPX7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A GPX7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000324096 GPX7 17699775 25416803 mrna cleavage,inhibition array technology TarBase
URS0000237E04 GPX7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000036B845 GPX7 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00003CC709 GPX7 23592263 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TCF25 GPX7 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GET3 GPX7 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GPX7 UBQLN4 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
GPX7 SGTA 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
GPX7 HSPA5 23123197 25348397 27898060 N/A physical interaction ComPPI,OmniPath
GPX7 HSPA9 25348397 N/A physical interaction ComPPI
GPX7 PDIA4 25348397 N/A physical interaction ComPPI
GPX7 EEF1A1 25348397 N/A physical interaction ComPPI
GPX7 EEF1A1P5 25348397 N/A physical interaction ComPPI
GPX7 DNAJB11 25348397 N/A physical interaction ComPPI
GPX7 H1-5 25348397 N/A physical interaction ComPPI
GPX7 CEP70 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
GPX7 ERO1A 25348397 N/A physical interaction ComPPI
GPX7 P4HB 25348397 N/A physical interaction ComPPI
GPX7 UTP6 25348397 N/A physical interaction ComPPI
GPX7 GAK 25348397 N/A physical interaction ComPPI
GPX7 PLPBP 25348397 N/A physical interaction ComPPI
GPX7 NFS1 25348397 N/A physical interaction ComPPI
GPX7 ZC3HC1 25348397 N/A physical interaction ComPPI
GPX7 LYRM4 25348397 N/A physical interaction ComPPI
GPX7 THYN1 25348397 N/A physical interaction ComPPI
GPX7 PHETA1 25348397 N/A physical interaction ComPPI
GPX7 THNSL1 25348397 N/A physical interaction ComPPI
GPX7 RIPK1 25348397 N/A physical interaction ComPPI
GPX7 MCTS1 25348397 N/A physical interaction ComPPI
GPX7 FTO 25348397 N/A physical interaction ComPPI
GPX7 PLEKHJ1 25348397 N/A physical interaction ComPPI
GPX7 CHMP1A 25348397 N/A physical interaction ComPPI
GPX7 PTPN11 25348397 N/A physical interaction ComPPI
GPX7 HSPA14 25348397 N/A physical interaction ComPPI
GPX7 SNX1 25348397 N/A physical interaction ComPPI
GPX7 C1ORF52 25348397 N/A physical interaction ComPPI
GPX7 SH3GL1 25348397 N/A physical interaction ComPPI
GPX7 PAPSS1 25348397 N/A physical interaction ComPPI
GPX7 FARSB 25348397 N/A physical interaction ComPPI
GPX7 PSME1 25348397 N/A physical interaction ComPPI
GPX7 SEC23IP 25348397 N/A physical interaction ComPPI
GPX7 EIF2AK2 25348397 N/A physical interaction ComPPI
GPX7 ZG16B 25348397 N/A physical interaction ComPPI
GPX7 ZC3HAV1L 25348397 N/A physical interaction ComPPI
GPX7 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPX7 NCALD 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPX7 SGTB 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
GPX7 NTAQ1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

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