GENE：BDH1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | BDH1 |
| FullNmae | 3-hydroxybutyrate dehydrogenase 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:1027 |
| EnsembleID | ENSG00000161267 |
| Uniprot | Q02338 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| BDH1 | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| BDH1 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| BDH1 | GO:0003858,GO:0003858,GO:0005739,GO:0005759,GO:0008202,GO:0043231,GO:0099617 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| BDH1 | hsa:622 | path:hsa00650 | Butanoate metabolism - Homo sapiens (human) |
| BDH1 | hsa:622 | path:hsa01100 | Metabolic pathways - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | BDH1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | BDH1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | BDH1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | BDH1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | BDH1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | BDH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00001CF056 | BDH1 | 21572407 23313552 23824327 24906430 25416803 27292025 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00004214BB | BDH1 | 24906430 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077AED | BDH1 | 21572407 23313552 23824327 24906430 25416803 27292025 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00003677B2 | BDH1 | 21572407 23313552 23824327 24906430 25416803 27292025 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS00000A057E | BDH1 | 21572407 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000035CC3E | BDH1 | 21572407 23313552 23824327 25416803 27418678 | mrna cleavage,inhibition | clip | TarBase |
| URS000058863C | BDH1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000009265 | BDH1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| HNRNPL | BDH1 | 25348397 | N/A | physical interaction | ComPPI |
| TNF | BDH1 | 25348397 | N/A | physical interaction | ComPPI |
| HDAC6 | BDH1 | 23752268 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD79A | BDH1 | 25348397 | N/A | physical interaction | ComPPI |
| IL13RA2 | BDH1 | 25348397 | N/A | physical interaction | ComPPI |
| APP | BDH1 | 25348397 | N/A | physical interaction | ComPPI |
| COX6B1 | BDH1 | 24234451 25348397 27499296 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |
| BDH1 | SLC15A1 | 25348397 | N/A | physical interaction | ComPPI |
| BDH1 | SLC18A1 | 25348397 | N/A | physical interaction | ComPPI |