Gene Information gene info

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GENE：ANK3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ANK3
FullNmae ankyrin 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:494
EnsembleID ENSG00000151150
Uniprot Q12955

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ANK3 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ANK3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ANK3 GO:0000281,GO:0005200,GO:0005515,GO:0005764,GO:0005783,GO:0005794,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005923,GO:0007009,GO:0007010,GO:0007165,GO:0007409,GO:0007528,GO:0008092,GO:0008093,GO:0009925,GO:0009986,GO:0010628,GO:0010650,GO:0010765,GO:0010960,GO:0014704,GO:0014731,GO:0016323,GO:0016328,GO:0016529,GO:0019228,GO:0030018,GO:0030315,GO:0030425,GO:0030507,GO:0030507,GO:0030674,GO:0031594,GO:0033268,GO:0034112,GO:0042383,GO:0043001,GO:0043005,GO:0043005,GO:0043034,GO:0043194,GO:0043194,GO:0043266,GO:0044325,GO:0044325,GO:0045184,GO:0045211,GO:0045296,GO:0045838,GO:0071286,GO:0071709,GO:0071709,GO:0072659,GO:0072659,GO:0072659,GO:0072659,GO:0072660,GO:0090314,GO:0099612,GO:1900827,GO:1902260,GO:2000651,GO:2001259

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ANK3 hsa:288 path:hsa05205 Proteoglycans in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 ANK3 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR ANK3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 ANK3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 ANK3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ANK3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ANK3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 ANK3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 ANK3 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ANK3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 ANK3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 ANK3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000028FD1A ANK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000046CDA6 ANK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 ANK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 ANK3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EED18 ANK3 25416803 25623948 mrna cleavage,inhibition western blot,immunocytochemistry,miRNA interference luciferase reporter assay TarBase

Source Target Pmid Interactiontype Methods Database
ANK3 SCN2A 25361965 interaction type N/A PTMCode2
SCN2A ANK3 25361965 interaction type N/A PTMCode2
ANK3 FADD 25361965 interaction type N/A PTMCode2
FADD ANK3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PCNA ANK3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM6 ANK3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
MCM2 ANK3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TIAM1 ANK3 25348397 N/A physical interaction ComPPI
PIK3R1 ANK3 14525934 16377635 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
SMAD2 ANK3 14525934 15231748 20195357 24234451 25348397 physical association two hybrid,display technology,physical interaction,two hybrid ComPPI,HPRD,IntAct
SMAD3 ANK3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FLNC ANK3 21223964 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
SCN5A ANK3 19805355 24234451 25348397 N/A pull down,physical interaction ComPPI,IntAct
FEZ1 ANK3 25348397 N/A physical interaction ComPPI
CDH1 ANK3 25348397 N/A physical interaction ComPPI
PLEC ANK3 21223964 24234451 25348397 colocalization confocal microscopy ComPPI,IntAct
HNRNPL ANK3 25348397 N/A physical interaction ComPPI
MAPK6 ANK3 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
FADD ANK3 14525934 14694156 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
MAPK8IP1 ANK3 25348397 N/A physical interaction ComPPI
RAPGEF5 ANK3 25348397 N/A physical interaction ComPPI
SCNN1B ANK3 11997395 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RNF2 ANK3 25348397 N/A physical interaction ComPPI
SPAG9 ANK3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
DOK4 ANK3 25348397 N/A physical interaction ComPPI
HIF1AN ANK3 25348397 N/A physical interaction ComPPI
AP3B1 ANK3 25348397 N/A two hybrid,pull down,physical interaction ComPPI
ANK3 SCN1B 11997395 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ANK3 SCN2A 12036953 14525934 25348397 27898060 N/A experimental interaction detection,in vivo ComPPI,HPRD,OmniPath
ANK3 SPTBN4 11807096 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
ANK3 KCNC1 12805291 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,OmniPath
ANK3 HOOK1 14525934 15823567 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD,OmniPath
ANK3 FAS 14525934 14694156 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
ANK3 PALM2 25348397 N/A physical interaction ComPPI
ANK3 PHAF1 25348397 N/A physical interaction ComPPI
ANK3 SRPK2 25348397 N/A physical interaction ComPPI
ANK3 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ANK3 KIF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ANK3 CTDSPL 25348397 N/A physical interaction ComPPI
ANK3 CHL1 25348397 N/A physical interaction ComPPI
ANK3 UXS1 25348397 N/A physical interaction ComPPI
ANK3 PWP1 25348397 N/A physical interaction ComPPI
ANK3 NEXN 25348397 N/A physical interaction ComPPI
ANK3 PROSER2 25348397 N/A physical interaction ComPPI
ANK3 ARHGAP22 25348397 N/A physical interaction ComPPI
ANK3 USP15 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ANK3 MCM4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ANK3 EPS15L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ANK3 IVNS1ABP 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ANK3 GTF3C4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ANK3 EZR 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CCT3 ANK3 24234451 30021884 physical association cross-linking study IntAct
HMGN1 ANK3 24234451 30021884 physical association cross-linking study IntAct
H1-10 ANK3 24234451 30021884 physical association cross-linking study IntAct

Visualization










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