Gene Information gene info

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GENE：CACNG2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CACNG2
FullNmae calcium voltage-gated channel auxiliary subunit gamma 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1406
EnsembleID ENSG00000166862
Uniprot Q9Y698

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CACNG2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CACNG2 GO:0005245,GO:0005515,GO:0005886,GO:0005891,GO:0006612,GO:0007528,GO:0009986,GO:0016247,GO:0019226,GO:0030666,GO:0032281,GO:0032281,GO:0034765,GO:0035255,GO:0036477,GO:0044300,GO:0051592,GO:0051899,GO:0051968,GO:0060081,GO:0060082,GO:0070588,GO:0098685,GO:0098686,GO:0098839,GO:0098943,GO:0098970,GO:0098978,GO:0099590,GO:0099645,GO:1904510,GO:2000311,GO:2000311

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CACNG2 hsa:10369 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
CACNG2 hsa:10369 path:hsa04260 Cardiac muscle contraction - Homo sapiens (human)
CACNG2 hsa:10369 path:hsa04261 Adrenergic signaling in cardiomyocytes - Homo sapiens (human)
CACNG2 hsa:10369 path:hsa04921 Oxytocin signaling pathway - Homo sapiens (human)
CACNG2 hsa:10369 path:hsa05410 Hypertrophic cardiomyopathy - Homo sapiens (human)
CACNG2 hsa:10369 path:hsa05412 Arrhythmogenic right ventricular cardiomyopathy - Homo sapiens (human)
CACNG2 hsa:10369 path:hsa05414 Dilated cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
YBX1 CACNG2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C CACNG2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 CACNG2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000016914 CACNG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 CACNG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 CACNG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003BD367 CACNG2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 CACNG2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GRIA1 CACNG2 25361965 interaction type N/A PTMCode2
CACNG2 GRIA1 25361965 interaction type N/A PTMCode2
DLG4 CACNG2 25361965 interaction type N/A PTMCode2
CACNG2 DLG4 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CSNK1D CACNG2 25348397 N/A physical interaction ComPPI
DLG4 CACNG2 11140673 11805122 12359873 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
PRKACA CACNG2 11805122 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
CSNK1E CACNG2 25348397 N/A physical interaction ComPPI
DLG2 CACNG2 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
GRIA2 CACNG2 25348397 N/A physical interaction ComPPI
GRIN1 CACNG2 25348397 N/A physical interaction ComPPI
DLG1 CACNG2 14525934 16637659 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
GRIA4 CACNG2 11140673 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
DLG3 CACNG2 14525934 16637659 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CCNT1 CACNG2 25348397 N/A physical interaction ComPPI
ITPR2 CACNG2 25348397 N/A physical interaction ComPPI
GOPC CACNG2 25348397 N/A physical interaction ComPPI
SRPK2 CACNG2 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
EPHA7 CACNG2 25348397 N/A physical interaction ComPPI
ATF1 CACNG2 25348397 N/A physical interaction ComPPI
CACNG2 PATJ 25348397 N/A in vitro ComPPI
CACNG2 GRIA1 11140673 14525934 25348397 N/A experimental interaction detection,physical interaction ComPPI,HPRD
CACNG2 APP 25348397 N/A physical interaction ComPPI
CACNG2 HBS1L 25348397 N/A physical interaction ComPPI
CACNG2 MTCH2 25348397 N/A physical interaction ComPPI
CACNG2 STAT3 25348397 N/A physical interaction ComPPI
CACNG2 MSTO1 25348397 N/A physical interaction ComPPI
CACNG2 PPIAL4G 25348397 N/A physical interaction ComPPI
HMGN1 CACNG2 24234451 30021884 physical association cross-linking study IntAct
PRKACA CACNG2 11805122 27898060 N/A N/A OmniPath

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