GENE:CCDC88C
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CCDC88C |
| FullNmae | coiled-coil domain containing 88C |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:19967 |
| EnsembleID | ENSG00000015133 |
| Uniprot | Q9P219 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CCDC88C | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CCDC88C | GO:0001932,GO:0001965,GO:0003383,GO:0005085,GO:0005109,GO:0005515,GO:0005737,GO:0005737,GO:0005813,GO:0007264,GO:0008017,GO:0030054,GO:0030054,GO:0030165,GO:0030705,GO:0031098,GO:0031122,GO:0031648,GO:0035567,GO:0042802,GO:0043621,GO:0051959,GO:0070161,GO:0090090 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| CCDC88C | hsa:440193 | path:hsa04310 | Wnt signaling pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | CCDC88C | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | CCDC88C | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CCDC88C | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | CCDC88C | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| FOXP3 | CCDC88C | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| RUNX1 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | CCDC88C | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000237AF9 | CCDC88C | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
| URS0000183BED | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | nucleotide sequence identification | TarBase |
| URS00000DDD35 | CCDC88C | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS0000042E1F | CCDC88C | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001CF056 | CCDC88C | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004A6E26 | CCDC88C | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002B2B5C | CCDC88C | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007A060 | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000F0F49 | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000171CD1 | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040EE1D | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000041CB9C | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007D64A | CCDC88C | 20371350 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000236310 | CCDC88C | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000018C928 | CCDC88C | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| GNAI3 | CCDC88C | 25348397 | N/A | physical interaction | ComPPI |
| BAG3 | CCDC88C | 25348397 | N/A | physical interaction | ComPPI |
| MAPK8 | CCDC88C | 21900206 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| PKM | CCDC88C | 25348397 | N/A | protein kinase assay | ComPPI |
| DVL1 | CCDC88C | 14525934 14750955 25348397 27898060 | N/A | two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| SMURF1 | CCDC88C | 25348397 | N/A | physical interaction | ComPPI |
| KATNA1 | CCDC88C | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| MCM7 | CCDC88C | 25348397 | N/A | physical interaction | ComPPI |
| LATS2 | CCDC88C | 25348397 | N/A | physical interaction | ComPPI |
| CCDC88C | ITSN2 | 25348397 | N/A | physical interaction | ComPPI |
| CCDC88C | APP | 25348397 | N/A | physical interaction | ComPPI |
| CCDC88C | NSD2 | 25348397 | N/A | physical interaction | ComPPI |
| CCDC88C | WDFY1 | 25348397 | N/A | physical interaction | ComPPI |
| CCDC88C | RNASE7 | 25348397 | N/A | physical interaction | ComPPI |
| CCDC88C | ALDH1L1 | 25348397 | N/A | physical interaction | ComPPI |
| DVL1P1 | CCDC88C | 23151663 27898060 | stimulant | N/A | OmniPath |
