Gene Information gene info

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GENE：PTPN5

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PTPN5
FullNmae protein tyrosine phosphatase non-receptor type 5
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9657
EnsembleID ENSG00000110786
Uniprot P54829

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PTPN5 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PTPN5 GO:0001784,GO:0004725,GO:0004725,GO:0005515,GO:0005654,GO:0005789,GO:0005829,GO:0005886,GO:0006470,GO:0007165,GO:0016020,GO:0019901,GO:0030054,GO:0035335

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PTPN5 hsa:84867 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRDM14 PTPN5 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA PTPN5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PTPN5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PTPN5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 PTPN5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PTPN5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PTPN5 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PTPN5 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MAPK1 PTPN5 25361965 interaction type N/A PTMCode2
PTPN5 MAPK1 25361965 interaction type N/A PTMCode2
PTPN5 FYN 25361965 interaction type N/A PTMCode2
FYN PTPN5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 PTPN5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
MAPK1IP1L PTPN5 25348397 N/A physical interaction ComPPI
ATP5PO PTPN5 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
RPN1 PTPN5 24234451 25348397 28330616 association pull down ComPPI,IntAct
ATP5F1B PTPN5 24234451 25348397 28330616 association pull down ComPPI,IntAct
CXCL9 PTPN5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
MARCHF5 PTPN5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZBTB5 PTPN5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
DLG4 PTPN5 25348397 N/A physical interaction ComPPI
MAPK1 PTPN5 14525934 24234451 25348397 28330616 9857190 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
MAPK3 PTPN5 14525934 24234451 25348397 28330616 9857190 association experimental interaction detection,pull down,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
RHOT2 PTPN5 24234451 25348397 28330616 association pull down ComPPI,IntAct
MAPK14 PTPN5 25348397 N/A physical interaction ComPPI
VAPA PTPN5 25348397 N/A physical interaction ComPPI
UBC PTPN5 25348397 N/A physical interaction ComPPI
RPS27A PTPN5 25348397 N/A physical interaction ComPPI
APOA1 PTPN5 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
SEC61A2 PTPN5 24234451 25348397 28330616 association pull down,physical interaction ComPPI,IntAct
PTPN5 FYN 11983687 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PTPN5 TERF1 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
PTPN5 SNX4 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN5 CCNQ 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PTPN5 VTI1B 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PTPN5 PRKN 25348397 N/A physical interaction ComPPI
PTPN5 ATP5PD 25348397 N/A physical interaction ComPPI
PTPN5 DCAKD 25348397 N/A physical interaction ComPPI
PTPN5 HLA-A 25348397 N/A physical interaction ComPPI
PTPN5 MOB1A 25348397 N/A physical interaction ComPPI
PTPN5 MOSPD2 25348397 N/A physical interaction ComPPI
PTPN5 TOMM70 25348397 N/A physical interaction ComPPI
PTPN5 MAPKAPK3 25348397 N/A physical interaction ComPPI
PTPN5 ATXN7L3B 25348397 N/A physical interaction ComPPI
PTPN5 TXNDC5 25348397 N/A physical interaction ComPPI
PTPN5 VAPB 25348397 N/A physical interaction ComPPI
PTPN5 BZW1 25348397 N/A physical interaction ComPPI
PTPN5 AURKA 25348397 N/A physical interaction ComPPI
PTPN5 MTCH2 25348397 N/A physical interaction ComPPI
PTPN5 DGKE 25348397 N/A physical interaction ComPPI
PTPN5 DHCR24 25348397 N/A physical interaction ComPPI
PTPN5 SEC61A1 25348397 N/A physical interaction ComPPI
PTPN5 TBL2 25348397 N/A physical interaction ComPPI
PTPN5 ALG1 25348397 N/A physical interaction ComPPI
PTPN5 ARL1 25348397 N/A physical interaction ComPPI
PTPN5 SLC27A4 25348397 N/A physical interaction ComPPI
PTPN5 DHCR7 25348397 N/A physical interaction ComPPI
PTPN5 FAF2 25348397 N/A physical interaction ComPPI
PTPN5 SLC35B1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN5 CYB561D2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN5 CLEC4G 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PTPN5 ATP5F1C 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 POMGNT1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 RTN4 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 ATP5PB 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 RPN2 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 PGRMC1 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 CERS2 24234451 25348397 28330616 association pull down ComPPI,IntAct
PTPN5 PPP2R2D 24234451 25348397 28330616 association pull down ComPPI,IntAct
TMEM51 PTPN5 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRKACA PTPN5 10908600 27898060 inhibition N/A OmniPath
PTPN5 FYN 11983687 27898060 inhibition N/A OmniPath
PTPN5 BAK1 20959805 27898060 stimulant N/A OmniPath
PTPN5 MAPK14 23932588 27898060 inhibition,stimulant N/A OmniPath
PTPN5 MAPK1 27898060 9857190 inhibition N/A OmniPath

Visualization










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