Gene Information gene info

  1. Home

GENE：SIGIRR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SIGIRR
FullNmae single Ig and TIR domain containing
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30575
EnsembleID ENSG00000185187
Uniprot Q6IA17

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SIGIRR immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SIGIRR GO:0001960,GO:0005515,GO:0005886,GO:0006953,GO:0007165,GO:0016020,GO:0031665,GO:0032682,GO:0043433

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SIGIRR SIGIRR 12925853 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIGIRR TLR4 12925853 15866876 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIGIRR MYD88 15866876 20364327 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIGIRR IRAK1 12925853 15866876 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIGIRR TRAF6 12925853 15866876 23180781 physical association anti tag coimmunoprecipitation InnateDB
IL1R1 SIGIRR 15866876 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIGIRR IL1R1 15866876 23180781 physical association anti tag coimmunoprecipitation InnateDB
SIGIRR PALM3 21187075 23180781 physical association anti tag coimmunoprecipitation,two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 SIGIRR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SIGIRR 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SIGIRR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SIGIRR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SIGIRR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SIGIRR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SIGIRR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SIGIRR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SP1 SIGIRR 21077278 trascriptional regulation,stimulation inferred by curator TFlink
DAND5 SIGIRR 21077278 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SIGIRR 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C770D SIGIRR 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TRAF6 SIGIRR 25361965 interaction type N/A PTMCode2
SIGIRR TRAF6 25361965 interaction type N/A PTMCode2
SIGIRR IRAK1 25361965 interaction type N/A PTMCode2
IRAK1 SIGIRR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
RPN1 SIGIRR 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TRAF6 SIGIRR 12925853 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
HNRNPL SIGIRR 25348397 N/A physical interaction ComPPI
IRAK1 SIGIRR 12925853 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
TLR4 SIGIRR 12925853 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SIGIRR TLR5 12925853 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SIGIRR TLR9 12925853 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
SIGIRR ENO2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SIGIRR IL1R1 12925853 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
SIGIRR APP 25348397 N/A physical interaction ComPPI
SIGIRR SIGIRR 12925853 14525934 N/A experimental interaction detection HPRD
PALM3 SIGIRR 21187075 27898060 N/A N/A OmniPath
TRAF6 SIGIRR 12925853 15866876 27898060 N/A N/A OmniPath
TLR4 SIGIRR 12925853 15866876 27898060 N/A N/A OmniPath
SIGIRR MYD88 15866876 20364327 27898060 inhibition N/A OmniPath
MYD88 SIGIRR 15866876 20364327 27898060 N/A N/A OmniPath
IL1R1 SIGIRR 12925853 15866876 27898060 N/A N/A OmniPath
IRAK1 SIGIRR 12925853 15866876 27898060 N/A N/A OmniPath
SIGIRR IRAK1 12925853 15866876 27898060 N/A N/A OmniPath

Visualization










  Return