Gene Information gene info

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GENE：C1QA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol C1QA
FullNmae complement C1q A chain
LocusType gene with protein product
Status Approved
HGNC_id HGNC:1241
EnsembleID ENSG00000173372
Uniprot P02745

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
C1QA immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
C1QA GO:0001540,GO:0001774,GO:0005515,GO:0005576,GO:0005576,GO:0005576,GO:0005581,GO:0005602,GO:0006956,GO:0006958,GO:0006958,GO:0007267,GO:0016322,GO:0045087,GO:0045202,GO:0048143,GO:0050808,GO:0062023,GO:0062167,GO:0098794,GO:0098883,GO:0150062,GO:0150064

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
C1QA hsa:712 path:hsa04148 Efferocytosis - Homo sapiens (human)
C1QA hsa:712 path:hsa04610 Complement and coagulation cascades - Homo sapiens (human)
C1QA hsa:712 path:hsa04936 Alcoholic liver disease - Homo sapiens (human)
C1QA hsa:712 path:hsa05020 Prion disease - Homo sapiens (human)
C1QA hsa:712 path:hsa05133 Pertussis - Homo sapiens (human)
C1QA hsa:712 path:hsa05142 Chagas disease - Homo sapiens (human)
C1QA hsa:712 path:hsa05150 Staphylococcus aureus infection - Homo sapiens (human)
C1QA hsa:712 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)
C1QA hsa:712 path:hsa05322 Systemic lupus erythematosus - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
C1QA ADIPOQ 18179772 23180781 physical association affinity chromatography technology InnateDB
ELANE C1QA 19506020 23180781 physical association two hybrid InnateDB
PTX3 C1QA 12645945 23180781 physical association solid phase assay InnateDB
C1QA PTX3 23180781 9407058 physical association solid phase assay InnateDB
PITX3 C1QA 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB
AGER C1QA 22386596 23180781 physical association unspecified method,surface plasmon resonance array InnateDB

Source Target Pmid Interactiontype Methods Database
EGR1 C1QA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 C1QA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 C1QA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 C1QA 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
C1QC C1QA 25361965 interaction type N/A PTMCode2
C1QA C1QC 25361965 interaction type N/A PTMCode2
C1QBP C1QA 25361965 interaction type N/A PTMCode2
C1QA C1QBP 25361965 interaction type N/A PTMCode2
C1QB C1QA 25361965 interaction type N/A PTMCode2
C1QA C1QB 25361965 interaction type N/A PTMCode2
SFTPA2 C1QA 25361965 interaction type N/A PTMCode2
C1QA SFTPA2 25361965 interaction type N/A PTMCode2
C1R C1QA 25361965 interaction type N/A PTMCode2
C1QA C1R 25361965 interaction type N/A PTMCode2
C1S C1QA 25361965 interaction type N/A PTMCode2
C1QA C1S 25361965 interaction type N/A PTMCode2
CD93 C1QA 25361965 interaction type N/A PTMCode2
C1QA CD93 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIAS2 C1QA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
SGTA C1QA 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1CC C1QA 25348397 N/A two hybrid,physical interaction ComPPI
SGTB C1QA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAC1 C1QA 25348397 N/A physical interaction ComPPI
APOA1 C1QA 15174051 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BAG6 C1QA 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPP1CA C1QA 22321011 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
LRP1 C1QA 21054788 24234451 25348397 physical association enzyme linked immunosorbent assay ComPPI,IntAct
C1QBP C1QA 14525934 25348397 27898060 8195709 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
SFTPA1 C1QA 11714829 14525934 25348397 27898060 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
C1QA COL2A1 14525934 25348397 27898060 8778019 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
C1QA C1QB 12960167 14525934 21054788 24234451 25348397 7240 association,physical association affinity chromatography technology,experimental interaction detection,x-ray crystallography,enzyme linked immunosorbent assay,in vitro,enzymatic footprinting ComPPI,HPRD,IntAct
C1QA C1QC 12960167 14525934 21054788 24234451 25348397 28325905 association,physical association affinity chromatography technology,experimental interaction detection,filter binding,x-ray crystallography,enzyme linked immunosorbent assay,in vitro ComPPI,HPRD,IntAct
C1QA CD93 14525934 25348397 9476117 N/A experimental interaction detection,in vitro ComPPI,HPRD
C1QA C1S 10878362 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
C1QA CR1 10528211 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
C1QA HRG 14525934 25348397 9184145 N/A experimental interaction detection,in vivo ComPPI,HPRD
C1QA C1R 10878362 14525934 2372546 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
C1QA CSPG4 14525934 25348397 27898060 9013976 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
C1QA PTX3 12645945 14525934 25348397 27898060 9407058 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
C1QA APCS 14525934 25348397 27898060 8417122 N/A experimental interaction detection,in vitro ComPPI,HPRD,OmniPath
C1QA HIPK3 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
C1QA CRP 25348397 N/A physical interaction ComPPI
C1QA DCN 1431141 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
C1QA FN1 14525934 25348397 27898060 6981115 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
C1QA SLC25A47 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
C1QA UBQLN2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
C1QA UBQLN1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
C1QA HSPB2 24234451 25348397 26465331 physical association two hybrid,physical interaction ComPPI,IntAct
C1QA NLGN3 25348397 N/A physical interaction ComPPI
GNPNAT1 C1QA 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
C1QA ADIPOQ 18179772 27898060 N/A N/A OmniPath

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