Gene Information gene info

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GENE：CISD1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CISD1
FullNmae CDGSH iron sulfur domain 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30880
EnsembleID ENSG00000122873
Uniprot Q9NZ45

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CISD1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CISD1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CISD1 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature
CISD1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CISD1 cuproptosis 38495196 Cuproptosis-related genes were manually curated, and differentially expressed cuproptosis-related genes (DECuGs) were identified.Then, the 16 DECuGs were obtained by the intersection of the 5018 DEGs and 63 cuproptosis-related genes. 63 cuproptosis-related genes
CISD1 cuproptosis 36685880 A total of 43 CRGs were manually identified and used to investigate the effects of cuproptosis in HNSC in current study. cuproptosis-related genes
CISD1 cuproptosis 36505872 A total of 44 cuproptosis-related genes were extracted from known literature. cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
CISD1 GO:0005739,GO:0005739,GO:0005739,GO:0005741,GO:0010506,GO:0030170,GO:0042802,GO:0042803,GO:0043457,GO:0046872,GO:0047801,GO:0051537,GO:0051537,GO:0106034

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RNF2 CISD1 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 CISD1 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
HIF1A CISD1 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CISD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA CISD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CISD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CISD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 CISD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CISD1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001A7F58 CISD1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000215483 CISD1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001EE123 CISD1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00004F24A9 CISD1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000299AD8 CISD1 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000192A75 CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003E1A9 CISD1 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPIB CISD1 25348397 N/A physical interaction ComPPI
STX12 CISD1 25348397 N/A physical interaction ComPPI
PSMD7 CISD1 25348397 N/A physical interaction ComPPI
NDUFAF4 CISD1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
VDAC1 CISD1 25348397 N/A physical interaction ComPPI
NR4A2 CISD1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CLTC CISD1 25348397 N/A physical interaction ComPPI
ABCE1 CISD1 25348397 N/A physical interaction ComPPI
VDAC2 CISD1 25348397 N/A physical interaction ComPPI
ANXA11 CISD1 25348397 N/A physical interaction ComPPI
BCAP31 CISD1 25348397 N/A physical interaction ComPPI
RNF2 CISD1 25348397 N/A physical interaction ComPPI
STX7 CISD1 25348397 N/A physical interaction ComPPI
PRKN CISD1 25348397 N/A physical interaction ComPPI
RPL6 CISD1 25348397 N/A physical interaction ComPPI
TOMM20 CISD1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
PRKAB1 CISD1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TOMM7 CISD1 25348397 N/A physical interaction ComPPI
MTX1 CISD1 25348397 N/A physical interaction ComPPI
TOMM40 CISD1 25348397 N/A physical interaction ComPPI
COX4I1 CISD1 25348397 N/A physical interaction ComPPI
VDAC3 CISD1 25348397 N/A physical interaction ComPPI
COQ9 CISD1 25348397 N/A physical interaction ComPPI
ATP5PD CISD1 25348397 N/A physical interaction ComPPI
SDHB CISD1 25348397 N/A physical interaction ComPPI
COX6B1 CISD1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
TSPO CISD1 25348397 N/A physical interaction ComPPI
OCIAD1 CISD1 25348397 N/A physical interaction ComPPI
NDUFA12 CISD1 25348397 N/A physical interaction ComPPI
NDUFA2 CISD1 25348397 N/A physical interaction ComPPI
PTPMT1 CISD1 25348397 N/A physical interaction ComPPI
TECR CISD1 25348397 N/A physical interaction ComPPI
NDUFA4 CISD1 25348397 N/A physical interaction ComPPI
CISD1 TTC30B 24234451 25348397 27173435 association,physical association physical interaction,tandem affinity purification,inference by socio-affinity scoring ComPPI,IntAct
CISD1 OPA3 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
CISD1 MICOS13 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct
ATP6V1C1 CISD1 25348397 N/A physical interaction ComPPI
HSCB CISD1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
CISD1 CISD1 17766439 17766440 24234451 N/A molecular sieving,x-ray crystallography,ion exchange chromatography IntAct

Source Target Pmid Interactiontype Methods Database
URS00009BCD08 CISD1 27087310 direct interaction,inhibition N/A NPInter

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