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GENE：DOCK4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DOCK4
FullNmae dedicator of cytokinesis 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19192
EnsembleID ENSG00000128512
Uniprot Q8N1I0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DOCK4 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DOCK4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DOCK4 GO:0005085,GO:0005085,GO:0005096,GO:0005515,GO:0005730,GO:0005737,GO:0005794,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0007264,GO:0016020,GO:0017124,GO:0030165,GO:0030971,GO:0031267,GO:0031267,GO:0032420,GO:0032421,GO:0060326,GO:0060326,GO:1904694,GO:1904754

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DOCK4 hsa:9732 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DOCK4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 DOCK4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DOCK4 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 DOCK4 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 DOCK4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000009262D DOCK4 22158624 rna interference,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS0000338542 DOCK4 19193853 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D DOCK4 22158624 25416803 mrna cleavage,inhibition experimental interaction detection,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS0000122ED0 DOCK4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000427B68 DOCK4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002DD349 DOCK4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000183BED DOCK4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC864 DOCK4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 DOCK4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB DOCK4 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004DA9DB DOCK4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 DOCK4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000321A1A DOCK4 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
NPM1 DOCK4 25348397 N/A physical interaction ComPPI
STAT1 DOCK4 25348397 N/A physical interaction ComPPI
GRB2 DOCK4 21706016 21988832 24234451 25348397 association,physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
YWHAB DOCK4 15324660 24234451 25348397 physical association coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 DOCK4 25348397 N/A physical interaction ComPPI
HNRNPL DOCK4 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ELMO1 DOCK4 25348397 N/A physical interaction ComPPI
GRK5 DOCK4 25348397 N/A physical interaction ComPPI
ARRB1 DOCK4 25348397 N/A physical interaction ComPPI
EGFR DOCK4 25348397 N/A physical interaction ComPPI
FASLG DOCK4 19807924 24234451 25348397 N/A phage display,physical interaction ComPPI,IntAct
MAGOH DOCK4 25348397 N/A physical interaction ComPPI
EIF4A3 DOCK4 25348397 N/A physical interaction ComPPI
HSPD1 DOCK4 24234451 30021884 physical association cross-linking study IntAct

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