Gene Information gene info

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GENE：FIG4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FIG4
FullNmae FIG4 phosphoinositide 5-phosphatase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16873
EnsembleID ENSG00000112367
Uniprot Q92562

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FIG4 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
FIG4 GO:0000139,GO:0004439,GO:0004722,GO:0005515,GO:0005811,GO:0006661,GO:0007033,GO:0007626,GO:0010008,GO:0031642,GO:0031901,GO:0031902,GO:0032288,GO:0034485,GO:0036092,GO:0043231,GO:0043231,GO:0043473,GO:0043813,GO:0043813,GO:0046856,GO:0048666

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
FIG4 hsa:9896 path:hsa00562 Inositol phosphate metabolism - Homo sapiens (human)
FIG4 hsa:9896 path:hsa01100 Metabolic pathways - Homo sapiens (human)
FIG4 hsa:9896 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
FIG4 hsa:9896 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR FIG4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FIG4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 FIG4 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 FIG4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000075AB14 FIG4 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075B0F6 FIG4 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000085F64 FIG4 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000076B539 FIG4 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000007F792 FIG4 23824327 24906430 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00000EC1BE FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 FIG4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004959F4 FIG4 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 FIG4 19536157 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
GORASP2 FIG4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CMAS FIG4 25348397 N/A physical interaction ComPPI
PIKFYVE FIG4 25348397 N/A physical interaction ComPPI
SNX27 FIG4 25348397 N/A physical interaction ComPPI
FIG4 SH2D3A 10716708 27898060 N/A N/A OmniPath

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