Gene Information gene info

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GENE：KRT2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KRT2
FullNmae keratin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:6439
EnsembleID ENSG00000172867
Uniprot P35908

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KRT2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KRT2 GO:0001533,GO:0003334,GO:0005200,GO:0005515,GO:0005615,GO:0005634,GO:0005737,GO:0005829,GO:0005882,GO:0008092,GO:0008544,GO:0016020,GO:0018149,GO:0030280,GO:0030280,GO:0031424,GO:0031424,GO:0032980,GO:0043616,GO:0045095,GO:0045109,GO:0045684,GO:0051546,GO:0070062

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PITX3 KRT2 22278372 23180781 physical association anti tag coimmunoprecipitation InnateDB
EED KRT2 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
ADRB2 KRT2 23180781 23798571 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 KRT2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 KRT2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 KRT2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KRT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KRT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 KRT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 KRT2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PIK3R2 KRT2 25348397 N/A physical interaction ComPPI
CUL5 KRT2 25348397 N/A physical interaction ComPPI
KRT19 KRT2 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
UBASH3B KRT2 25348397 N/A physical interaction ComPPI
KRT38 KRT2 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
KRT5 KRT2 25348397 N/A physical interaction ComPPI
KRT2 KRT31 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
KRT2 KRT40 24234451 25348397 25416956 25910212 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
KRT2 EVPL 14525934 25348397 8999895 N/A experimental interaction detection,in vivo ComPPI,HPRD
KRT2 SMAD3 14525934 15527767 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
KRT2 KAT2A 25348397 N/A physical interaction ComPPI
KRT2 POU5F1 25348397 N/A physical interaction ComPPI
KRT2 HDGF 25348397 N/A physical interaction ComPPI
KRT2 CUL3 25348397 N/A physical interaction ComPPI
KRT2 CUL4A 25348397 N/A physical interaction ComPPI
KRT2 CUL4B 25348397 N/A physical interaction ComPPI
KRT2 CUL2 25348397 N/A physical interaction ComPPI
KRT2 CUL1 25348397 N/A physical interaction ComPPI
KRT2 COPS5 25348397 N/A physical interaction ComPPI
KRT2 COPS6 25348397 N/A physical interaction ComPPI
KRT2 DCUN1D1 25348397 N/A physical interaction ComPPI
KRT2 CAND1 25348397 N/A physical interaction ComPPI
KRT2 NEDD8 25348397 N/A physical interaction ComPPI
KRT2 INPPL1 25348397 N/A physical interaction ComPPI
KRT2 CBL 25348397 N/A physical interaction ComPPI
KRT2 GRB2 25348397 N/A physical interaction ComPPI
KRT2 SHC1 25348397 N/A physical interaction ComPPI
KRT2 CRK 25348397 N/A physical interaction ComPPI
KRT2 EPS15 25348397 N/A physical interaction ComPPI
KRT2 AP2M1 25348397 N/A physical interaction ComPPI
KRT2 KRT1 25348397 N/A physical interaction ComPPI
KRT2 KRT10 25348397 N/A physical interaction ComPPI
KRT2 MAGOH 25348397 N/A physical interaction ComPPI
KRT2 EIF4A3 25348397 N/A physical interaction ComPPI
KRT2 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
KRT2 VCAM1 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
KRT2 IQCB1 25348397 N/A physical interaction ComPPI
KRT2 PAN2 25348397 N/A physical interaction ComPPI
KRT2 ADRB2 25348397 N/A physical interaction ComPPI
KRT2 LGR4 25348397 N/A physical interaction ComPPI
KRT2 KRT13 24234451 25348397 25910212 physical association physical interaction,two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
KRT2 MDM2 25348397 N/A physical interaction ComPPI
KRT2 EED 25348397 N/A physical interaction ComPPI
KRT2 RPS6KB2 25348397 N/A physical interaction ComPPI
KRT2 HNRNPA1 25348397 N/A physical interaction ComPPI
KRT2 KRT77 25348397 N/A physical interaction ComPPI
KRT2 PRSS1 25348397 N/A physical interaction ComPPI
KRT2 SFN 25348397 N/A physical interaction ComPPI
KRT2 EWSR1 25348397 N/A physical interaction ComPPI
KRT2 YEATS4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KRT2 CRY1 25348397 N/A physical interaction ComPPI
KRT2 MCM2 25348397 N/A physical interaction ComPPI
KRT2 MCM5 25348397 N/A physical interaction ComPPI
KRT2 RC3H1 25348397 N/A physical interaction ComPPI
KRT2 EGFR 25348397 N/A physical interaction ComPPI
KRT2 MTM1 25348397 N/A physical interaction ComPPI
KRT2 CYLD 25348397 N/A physical interaction ComPPI
KRT2 LASP1 25348397 N/A physical interaction ComPPI
KRT2 KEAP1 25348397 N/A physical interaction ComPPI
KRT2 PPP2R2B 19156129 24234451 25348397 association anti tag coimmunoprecipitation,pull down ComPPI,IntAct
KRT2 MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT2 MAP1LC3B 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT2 GABARAPL2 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT2 GABARAPL1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT2 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT2 PPP1R15A 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
KRT2 KRT15 24234451 25348397 25910212 physical association two hybrid,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,split luciferase complementation,validated two hybrid ComPPI,IntAct
KRT2 KRT33B 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT2 KRT16 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT2 KRT35 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT2 KRT25 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
KRT2 KRT27 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRAF6 KRT2 25348397 N/A physical interaction ComPPI
METTL3 KRT2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
WTAP KRT2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
METTL14 KRT2 24234451 29507755 association anti tag coimmunoprecipitation IntAct
ATF2 KRT2 10085140 27898060 N/A N/A OmniPath
KRT2 ATF2 10085140 27898060 N/A N/A OmniPath
IRF3 KRT2 14729983 27898060 N/A N/A OmniPath
KRT2 IRF7 14729983 27898060 N/A N/A OmniPath
EP300 KRT2 19419955 27898060 N/A N/A OmniPath
ISG15 KRT2 16009940 27898060 N/A N/A OmniPath
NLK KRT2 21988832 27898060 N/A N/A OmniPath

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