GENE:NOS1AP
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | NOS1AP |
| FullNmae | nitric oxide synthase 1 adaptor protein |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:16859 |
| EnsembleID | ENSG00000198929 |
| Uniprot | O75052 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| NOS1AP | immunogenic | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| NOS1AP | GO:0002102,GO:0003062,GO:0005515,GO:0005634,GO:0005739,GO:0005829,GO:0005901,GO:0010628,GO:0010750,GO:0030018,GO:0030175,GO:0030315,GO:0031965,GO:0033017,GO:0042383,GO:0045428,GO:0045429,GO:0048471,GO:0050998,GO:0050999,GO:0051000,GO:0060307,GO:0060307,GO:0070161,GO:0098901,GO:0098901,GO:0098974,GO:0098974,GO:0098974,GO:0098978,GO:0098978,GO:1901381,GO:1901841,GO:1902261,GO:1902514,GO:1902514,GO:1903762,GO:2000170 |
KEGG Annotation:
| GeneSymbol | GeneID | Pathway | Pathway Name |
|---|---|---|---|
| NOS1AP | hsa:9722 | path:hsa04713 | Circadian entrainment - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | NOS1AP | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| GATA2 | NOS1AP | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| TFAP2C | NOS1AP | 20629094 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| TP73 | NOS1AP | 21245298 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| FOXP3 | NOS1AP | 20554955 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| SMARCA4 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TRIM28 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TAL1 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | NOS1AP | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000BE495 | NOS1AP | 23592263 23622248 25416803 | mrna cleavage,inhibition | clip,clash | TarBase |
| URS00003CF1AD | NOS1AP | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000023F008 | NOS1AP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000585553 | NOS1AP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000032D69B | NOS1AP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003E5E03 | NOS1AP | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002004E0 | NOS1AP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000040780F | NOS1AP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000DD591 | NOS1AP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003B59DF | NOS1AP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000085F64 | NOS1AP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | NOS1AP | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001925C1 | NOS1AP | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001799A3 | NOS1AP | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000364FEF | NOS1AP | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075AB35 | NOS1AP | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000284586 | NOS1AP | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000019D79B | NOS1AP | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| OIP5 | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| PCNA | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| PTPRH | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| RYBP | NOS1AP | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| KEAP1 | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| NHP2 | NOS1AP | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| SYN1 | NOS1AP | 11867766 14525934 25348397 | N/A | experimental interaction detection,physical interaction,in vivo | ComPPI,HPRD |
| BTRC | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| PLK1 | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| LRP1 | NOS1AP | 10827173 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| LRP8 | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| RALA | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| MDK | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | RASD1 | 11086993 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| NOS1AP | NOS1 | 14525934 25348397 9459447 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| NOS1AP | LRP2 | 10827173 14525934 25348397 | N/A | experimental interaction detection,physical interaction,two hybrid | ComPPI,HPRD |
| NOS1AP | APP | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | TRAF4 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| NOS1AP | EAF1 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | AP2M1 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | AKNAD1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| NOS1AP | NKAP | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| NOS1AP | FYN | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| NOS1AP | HSPD1 | 24234451 25348397 25814554 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| NOS1AP | XPO1 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | RAB5C | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | SNCA | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | YWHAH | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | PRPF4 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | TOMM40 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | RNPS1 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | NAF1 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | KLC3 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | PTPRJ | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | NKAPD1 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | ZCCHC17 | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | PNN | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | PIP4K2A | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | TRPC4AP | 25348397 | N/A | physical interaction | ComPPI |
| NOS1AP | PTPRN | 11043403 24234451 25348397 | N/A | pull down | ComPPI,IntAct |
| DDX41 | NOS1AP | 25348397 | N/A | physical interaction | ComPPI |
| FAM133A | NOS1AP | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| H2BC21 | NOS1AP | 24234451 30021884 | physical association | cross-linking study | IntAct |
