Gene Information gene info

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GENE：NSMCE2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NSMCE2
FullNmae NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26513
EnsembleID ENSG00000156831
Uniprot Q96MF7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NSMCE2 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NSMCE2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NSMCE2 GO:0000722,GO:0000724,GO:0000724,GO:0000724,GO:0000781,GO:0000781,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0007049,GO:0008270,GO:0016604,GO:0016605,GO:0016925,GO:0016925,GO:0016925,GO:0016925,GO:0019789,GO:0019789,GO:0030915,GO:0030915,GO:0030915,GO:0032204,GO:0034184,GO:0045842,GO:0051301,GO:0061665,GO:0090398,GO:0140588

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR NSMCE2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
GATA1 NSMCE2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NSMCE2 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 NSMCE2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C NSMCE2 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 NSMCE2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NSMCE2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002FB065 NSMCE2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000032FC1A NSMCE2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000049704B NSMCE2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000070B1D NSMCE2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TXLNA NSMCE2 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
NSMCE2 SMC6 18086888 24234451 25348397 26496610 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE2 RAD21 25348397 N/A physical interaction ComPPI
NSMCE2 STAG2 25348397 N/A physical interaction ComPPI
NSMCE2 SMC1A 25348397 N/A physical interaction ComPPI
NSMCE2 SMC3 25348397 N/A physical interaction ComPPI
NSMCE2 PDS5A 25348397 N/A physical interaction ComPPI
NSMCE2 PDS5B 25348397 N/A physical interaction ComPPI
NSMCE2 WAPL 25348397 N/A physical interaction ComPPI
NSMCE2 ETV1 25348397 N/A physical interaction ComPPI
NSMCE2 PAN2 25348397 N/A physical interaction ComPPI
NSMCE2 USP28 25348397 N/A physical interaction ComPPI
NSMCE2 EWSR1 25348397 N/A physical interaction ComPPI
NSMCE2 ILK 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE2 SORT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE2 NIPSNAP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE2 SYNCRIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NSMCE2 HNRNPL 25348397 N/A physical interaction ComPPI
NSMCE2 BRCA1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
UBE2I NSMCE2 15738391 19748359 22562154 27898060 N/A N/A OmniPath
NSMCE2 TERF1 19308705 27898060 stimulant N/A OmniPath
NSMCE2 TERF2 19308705 27898060 stimulant N/A OmniPath
NSMCE2 TERF2IP 19308705 27898060 stimulant N/A OmniPath
NSMCE2 TINF2 19308705 27898060 stimulant N/A OmniPath
NSMCE2 SMC6 15738391 16055714 18086888 22751501 26344197 26496610 27898060 stimulant N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009AF5E1 NSMCE2 27087310 direct interaction,inhibition N/A NPInter

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