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GENE：PPCDC

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPCDC
FullNmae phosphopantothenoylcysteine decarboxylase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28107
EnsembleID ENSG00000138621
Uniprot Q96CD2

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPCDC immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPCDC GO:0004633,GO:0004633,GO:0005515,GO:0005829,GO:0010181,GO:0010181,GO:0015937,GO:0015937,GO:0015937,GO:0042802,GO:0042802,GO:0071513

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPCDC hsa:60490 path:hsa00770 Pantothenate and CoA biosynthesis - Homo sapiens (human)
PPCDC hsa:60490 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PPCDC hsa:60490 path:hsa01240 Biosynthesis of cofactors - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PPCDC 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 PPCDC 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 PPCDC 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 PPCDC 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR PPCDC 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
TXN2 PPCDC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PSMA1 PPCDC 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPIG PPCDC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
LNX1 PPCDC 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DBI PPCDC 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
NTAQ1 PPCDC 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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