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GENE：PPIL2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PPIL2
FullNmae peptidylprolyl isomerase like 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9261
EnsembleID ENSG00000100023
Uniprot Q13356

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PPIL2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PPIL2 GO:0000209,GO:0000209,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0005737,GO:0005796,GO:0005886,GO:0006397,GO:0006457,GO:0008380,GO:0034450,GO:0061630,GO:0061630,GO:0071013,GO:0072659

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PPIL2 hsa:23759 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PPIL2 EGR1 20690147 23180781 physical association anti tag coimmunoprecipitation InnateDB
TRIM23 PPIL2 23180781 25416956 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PPIL2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 PPIL2 19735555 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 PPIL2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PPIL2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000041CB9C PPIL2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000001EB3 PPIL2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000021D7C8 PPIL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EEE35 PPIL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 PPIL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 PPIL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C PPIL2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF PPIL2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BSG PPIL2 25361965 interaction type N/A PTMCode2
PPIL2 BSG 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIM2 PPIL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMNA PPIL2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
CALM1 PPIL2 25348397 N/A physical interaction ComPPI
H2BC4 PPIL2 25348397 N/A physical interaction ComPPI
MAPK14 PPIL2 25348397 N/A physical interaction ComPPI
HSP90AA1 PPIL2 14525934 15189447 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PDGFRA PPIL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NTRK1 PPIL2 25348397 N/A physical interaction ComPPI
NAGK PPIL2 25348397 N/A physical interaction ComPPI
TRIM23 PPIL2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CDK8 PPIL2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
H3C1 PPIL2 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BAIAP2 PPIL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLC3 PPIL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
KLC2 PPIL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIL2 CRNKL1 14525934 15189447 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
PPIL2 HSP90AA2P 25348397 N/A physical interaction ComPPI
PPIL2 BSG 14525934 15946952 25348397 27898060 N/A experimental interaction detection,physical interaction ComPPI,HPRD,OmniPath
PPIL2 APP 25348397 N/A physical interaction ComPPI
PPIL2 PRCC 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PPIL2 ZNF830 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PPIL2 FGL1 25348397 N/A physical interaction ComPPI
PPIL2 FKBP6 25348397 N/A physical interaction ComPPI
PPIL2 H2BC11 25348397 N/A physical interaction ComPPI
PPIL2 VPS26B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIL2 KANSL2 24234451 25348397 26496610 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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