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GENE：PRPF3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRPF3
FullNmae pre-mRNA processing factor 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17348
EnsembleID ENSG00000117360
Uniprot O43395

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRPF3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRPF3 GO:0000244,GO:0000375,GO:0000398,GO:0000398,GO:0000398,GO:0003723,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005681,GO:0005829,GO:0006397,GO:0008380,GO:0015030,GO:0016607,GO:0042802,GO:0046540,GO:0046540,GO:0071005

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRPF3 hsa:9129 path:hsa03040 Spliceosome - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DVL3 PRPF3 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 PRPF3 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PRPF3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PRPF3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
EGR1 PRPF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRPF3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
CSNK2A1 PRPF3 22135298 phosphorylation N/A PhosphoSite
CHEK1 PRPF3 22135298 phosphorylation N/A PhosphoSite
CDK2 PRPF3 22135298 phosphorylation N/A PhosphoSite
USP39 PRPF3 25361965 interaction type N/A PTMCode2
PRPF3 USP39 25361965 interaction type N/A PTMCode2
USP15 PRPF3 25361965 interaction type N/A PTMCode2
PRPF3 USP15 25361965 interaction type N/A PTMCode2
SF3A2 PRPF3 25361965 interaction type N/A PTMCode2
PRPF3 SF3A2 25361965 interaction type N/A PTMCode2
USP4 PRPF3 25361965 interaction type N/A PTMCode2
PRPF3 USP4 25361965 interaction type N/A PTMCode2
PRPF3 PRPF4 25361965 interaction type N/A PTMCode2
PRPF4 PRPF3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
MFAP1 PRPF3 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SF3A3 PRPF3 25348397 N/A physical interaction ComPPI
TXLNA PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SNRPC PRPF3 25348397 N/A physical interaction ComPPI
GOLGA2 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
BCAS2 PRPF3 25348397 N/A physical interaction ComPPI
SLU7 PRPF3 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SNRPB PRPF3 25348397 N/A physical interaction ComPPI
CDC5L PRPF3 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CHCHD2 PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
ZBTB8A PRPF3 25348397 N/A physical interaction ComPPI
DPY30 PRPF3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TXNL4A PRPF3 25348397 N/A physical interaction ComPPI
CD2BP2 PRPF3 25348397 N/A physical interaction ComPPI
SNRPA1 PRPF3 25348397 N/A physical interaction ComPPI
PCBP1 PRPF3 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SNRPF PRPF3 25348397 N/A physical interaction ComPPI
LSM2 PRPF3 25348397 N/A physical interaction ComPPI
SNRPG PRPF3 25348397 N/A physical interaction ComPPI
LSM3 PRPF3 25348397 N/A physical interaction ComPPI
LSM6 PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SNRPD1 PRPF3 25348397 N/A physical interaction ComPPI
LSM1 PRPF3 25348397 N/A physical interaction ComPPI
SNIP1 PRPF3 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CCDC85B PRPF3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GPRASP2 PRPF3 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
SF3A2 PRPF3 17332742 24234451 25348397 physical association affinity chromatography technology,physical interaction ComPPI,IntAct
SNRNP70 PRPF3 25348397 N/A physical interaction ComPPI
JUN PRPF3 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RBM39 PRPF3 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SF3B1 PRPF3 25348397 N/A physical interaction ComPPI
U2AF2 PRPF3 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
TUBG1 PRPF3 25348397 N/A physical interaction ComPPI
LSM8 PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NTRK1 PRPF3 25348397 N/A physical interaction ComPPI
RNH1 PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
KIFAP3 PRPF3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP7 PRPF3 25348397 N/A physical interaction ComPPI
HNRNPL PRPF3 25348397 N/A physical interaction ComPPI
PABPC1 PRPF3 25348397 N/A physical interaction ComPPI
XAB2 PRPF3 25348397 N/A physical interaction ComPPI
RABEP1 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
USP4 PRPF3 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NEDD8 PRPF3 18274552 24234451 25348397 association tandem affinity purification ComPPI,IntAct
DVL2 PRPF3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
SNRPD3 PRPF3 25348397 N/A physical interaction ComPPI
SMNDC1 PRPF3 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
WBP4 PRPF3 16055720 24234451 25348397 physical association pull down,physical interaction ComPPI,IntAct
SON PRPF3 25348397 N/A physical interaction ComPPI
SEPTIN2 PRPF3 25348397 N/A physical interaction ComPPI
SF3A1 PRPF3 25348397 N/A physical interaction ComPPI
CASQ2 PRPF3 25348397 N/A physical interaction ComPPI
SUPT16H PRPF3 25348397 N/A physical interaction ComPPI
MMS19 PRPF3 25348397 N/A physical interaction ComPPI
SSX2IP PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
WWOX PRPF3 25348397 N/A physical interaction ComPPI
SHKBP1 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
VCAM1 PRPF3 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
H3C1 PRPF3 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
ZFPM2 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF6 PRPF3 25348397 N/A physical interaction ComPPI
FOXA1 PRPF3 25348397 N/A physical interaction ComPPI
SART3 PRPF3 12374753 14525934 15314151 15452143 19615732 20595234 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct,OmniPath
TFIP11 PRPF3 25348397 N/A physical interaction ComPPI
SNRPD2 PRPF3 25348397 N/A physical interaction ComPPI
LSM4 PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
LSM5 PRPF3 25348397 N/A physical interaction ComPPI
ELAVL1 PRPF3 25348397 N/A physical interaction ComPPI
PRPF4 PRPF3 16723661 19615732 22939629 24234451 25348397 26344197 26496610 27898060 9826507 association,physical association anti tag coimmunoprecipitation,physical interaction,inference by socio-affinity scoring ComPPI,IntAct,OmniPath
SRSF5 PRPF3 25348397 N/A physical interaction ComPPI
MPHOSPH6 PRPF3 25348397 N/A physical interaction ComPPI
DVL3 PRPF3 14525934 16189514 24234451 25348397 physical association two hybrid,pull down,physical interaction,two hybrid pooling approach,two hybrid ComPPI,HPRD,IntAct
SNRNP200 PRPF3 25348397 N/A physical interaction ComPPI
SNU13 PRPF3 25348397 N/A physical interaction ComPPI
BRCA1 PRPF3 25348397 N/A physical interaction ComPPI
ZRANB1 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ILKAP PRPF3 25348397 N/A physical interaction ComPPI
ALYREF PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SRSF7 PRPF3 25348397 N/A physical interaction ComPPI
RBM42 PRPF3 25348397 N/A physical interaction ComPPI
TRA2A PRPF3 25348397 N/A physical interaction ComPPI
AURKB PRPF3 25348397 N/A physical interaction ComPPI
PLRG1 PRPF3 25348397 N/A physical interaction ComPPI
SEPTIN7 PRPF3 25348397 N/A physical interaction ComPPI
SRRM2 PRPF3 25348397 N/A physical interaction ComPPI
RNPS1 PRPF3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CARD10 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RPS10 PRPF3 25348397 N/A physical interaction ComPPI
CEP250 PRPF3 25348397 N/A physical interaction ComPPI
HNRNPM PRPF3 25348397 N/A physical interaction ComPPI
RAB4B PRPF3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPIH PRPF3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
TARDBP PRPF3 25348397 N/A physical interaction ComPPI
THRAP3 PRPF3 25348397 N/A physical interaction ComPPI
OSBPL3 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SRRM1 PRPF3 25348397 N/A physical interaction ComPPI
SF3B3 PRPF3 25348397 N/A physical interaction ComPPI
LZTS1 PRPF3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF4A3 PRPF3 25348397 N/A physical interaction ComPPI
PRPF3 GTPBP3 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
PRPF3 USP15 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF3 USP39 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF3 MEPCE 25348397 N/A physical interaction ComPPI
PRPF3 PRPF19 25348397 N/A physical interaction ComPPI
PRPF3 PRPF8 25348397 N/A physical interaction ComPPI
PRPF3 SART1 25348397 N/A physical interaction ComPPI
PRPF3 PRPF31 25348397 N/A physical interaction ComPPI
PRPF3 RBM25 25348397 N/A physical interaction ComPPI
PRPF3 PATL1 25348397 N/A physical interaction ComPPI
PRPF3 CDK13 25348397 N/A physical interaction ComPPI
PRPF3 NOP58 25348397 N/A physical interaction ComPPI
PRPF3 NNT 25348397 N/A physical interaction ComPPI
PRPF3 FBL 25348397 N/A physical interaction ComPPI
PRPF3 SF3B2 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PRPF3 CTNNBL1 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRPF3 FRA10AC1 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRPF3 NKAP 22365833 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
PRPF3 ZCCHC10 22365833 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
PRPF3 LIN28A 25348397 N/A physical interaction ComPPI
PRPF3 TRIM39 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
PRPF3 FAM9B 24234451 25348397 25416956 25910212 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
PRPF3 OBSL1 25348397 N/A physical interaction ComPPI
PRPF3 DDX23 25348397 N/A physical interaction ComPPI
PRPF3 CENATAC 25348397 N/A physical interaction ComPPI
PRPF3 SNRNP40 25348397 N/A physical interaction ComPPI
PRPF3 RBM26 25348397 N/A physical interaction ComPPI
PRPF3 UTP20 25348397 N/A physical interaction ComPPI
PRPF3 MIA 25348397 N/A physical interaction ComPPI
PRPF3 POU5F1 25348397 N/A physical interaction ComPPI
PRPF3 ZNF131 25348397 N/A physical interaction ComPPI
PRPF3 TUT1 25348397 N/A physical interaction ComPPI
PRPF3 AKAP7 25348397 N/A physical interaction ComPPI
PRPF3 ZGPAT 25348397 N/A physical interaction ComPPI
PRPF3 SNRPN 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PRPF3 SNRPE 25348397 N/A physical interaction ComPPI
PRPF3 SNRPGP15 25348397 N/A physical interaction ComPPI
PRPF3 TMOD3 25348397 N/A physical interaction ComPPI
PRPF3 FBXO11 25348397 N/A physical interaction ComPPI
PRPF3 RPL26L1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRPF3 OLA1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRPF3 RPL32 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRPF3 FAU 25348397 N/A physical interaction ComPPI
PRPF3 FAU 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
PRPF3 NCL 25348397 N/A physical interaction ComPPI
PRPF3 PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PRPF3 MCM7 23764002 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
PRPF3 NACC1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF3 NKAPD1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF3 RNF151 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF3 CEP70 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF3 CCDC125 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF3 HSF2BP 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRPF3 PSMD3 24234451 25348397 25910212 physical association two hybrid array,two hybrid bait and prey pooling approach,validated two hybrid ComPPI,IntAct
SNRNP27 PRPF3 25348397 N/A physical interaction ComPPI
PRPF3 PRPF3 22365833 24234451 physical association anti tag coimmunoprecipitation,two hybrid IntAct
MKI67 PRPF3 24234451 26949251 association anti tag coimmunoprecipitation IntAct
CSNK2A1 PRPF3 17932117 27898060 stimulant N/A OmniPath

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