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GENE：PRR5L

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRR5L
FullNmae proline rich 5 like
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25878
EnsembleID ENSG00000135362
Uniprot Q6MZQ0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRR5L immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRR5L GO:0001933,GO:0001934,GO:0005515,GO:0009968,GO:0010762,GO:0031625,GO:0031932,GO:0031932,GO:0034599,GO:0038203,GO:0038203,GO:0061014,GO:0090316

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PRR5L hsa:79899 path:hsa04150 mTOR signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MLST8 PRR5L 17461779 23180781 physical association anti tag coimmunoprecipitation InnateDB
PRR5L MTOR 17461779 18030348 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,pull down,in-gel kinase assay InnateDB
RICTOR PRR5L 17461779 18030348 18505677 23180781 phosphorylation reaction,physical association anti tag coimmunoprecipitation,two hybrid,pull down,in-gel kinase assay InnateDB
PRR5L MAPKAP1 17461779 18030348 23180781 physical association anti tag coimmunoprecipitation,pull down InnateDB
PRR5L RPTOR 18030348 23180781 phosphorylation reaction in-gel kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR PRR5L 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PRR5L 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 PRR5L 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 PRR5L 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PRR5L 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000544FF1 PRR5L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 PRR5L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00001310DE PRR5L 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS0000081D1E PRR5L 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
FHL3 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
FHL2 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ZFP36 PRR5L 25348397 N/A physical interaction ComPPI
EFHC1 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MTOR PRR5L 17461779 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MLST8 PRR5L 17461779 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
MLH1 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PHAF1 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RICTOR PRR5L 17461779 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
USP2 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SCNM1 PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MAPKAP1 PRR5L 17461779 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HSF2BP PRR5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRR5L ZMYND12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRR5L KANK2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRR5L MORN3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PRR5L MLST8 17461779 27898060 N/A N/A OmniPath
MLST8 PRR5L 17461779 27898060 N/A N/A OmniPath
PRR5L RICTOR 17461779 18030348 18505677 21964062 27898060 N/A N/A OmniPath
RICTOR PRR5L 17461779 18030348 18505677 21964062 27898060 N/A N/A OmniPath
RPTOR PRR5L 18030348 27898060 N/A N/A OmniPath
MTOR PRR5L 17461779 18030348 27898060 N/A N/A OmniPath
PRR5L MTOR 17461779 18030348 27898060 N/A N/A OmniPath

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