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GENE：SIL1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SIL1
FullNmae SIL1 nucleotide exchange factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24624
EnsembleID ENSG00000120725
Uniprot Q9H173

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SIL1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SIL1 GO:0000774,GO:0000774,GO:0005515,GO:0005615,GO:0005783,GO:0005783,GO:0005783,GO:0005788,GO:0006457,GO:0006613,GO:0006886,GO:0042802,GO:0051082

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SIL1 hsa:64374 path:hsa04141 Protein processing in endoplasmic reticulum - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SIL1 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SIL1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 SIL1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SIL1 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
TFAP2C SIL1 20629094 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 SIL1 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SIL1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003D5391 SIL1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SIL1 SMAD9 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIL1 HSPA5 12356756 14525934 25348397 25877869 27898060 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,OmniPath
SIL1 CCND3 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SIL1 FBXO6 25348397 N/A physical interaction ComPPI
SIL1 UBQLN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SIL1 PON2 25348397 N/A physical interaction ComPPI
SIL1 PSMD8 25348397 N/A physical interaction ComPPI
SIL1 CNTNAP1 25348397 N/A physical interaction ComPPI
SIL1 UBR1 25348397 N/A physical interaction ComPPI
SIL1 TDGF1 25348397 N/A physical interaction ComPPI
SIL1 UBR2 25348397 N/A physical interaction ComPPI
SIL1 COL14A1 25348397 N/A physical interaction ComPPI
SIL1 OMA1 25348397 N/A physical interaction ComPPI
SIL1 PTPRO 25348397 N/A physical interaction ComPPI
SIL1 HNRNPL 25348397 N/A physical interaction ComPPI

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