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GENE：UBE2E3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol UBE2E3
FullNmae ubiquitin conjugating enzyme E2 E3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:12479
EnsembleID ENSG00000170035
Uniprot Q969T4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
UBE2E3 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
UBE2E3 GO:0004842,GO:0005515,GO:0005524,GO:0005634,GO:0005654,GO:0005829,GO:0061631,GO:0070534,GO:0070534,GO:0070936,GO:0070936,GO:0070979,GO:0070979

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
UBE2E3 hsa:10477 path:hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
UBA2 UBE2E3 10187858 23180781 other modification enzymatic study InnateDB
NFKBIA UBE2E3 10187858 23180781 other modification sumoylation reaction InnateDB

Source Target Pmid Interactiontype Methods Database
AR UBE2E3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 UBE2E3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 UBE2E3 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 UBE2E3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 UBE2E3 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 UBE2E3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 UBE2E3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B UBE2E3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000040EE1D UBE2E3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000017EE98 UBE2E3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC UBE2E3 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 UBE2E3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000028DE3F UBE2E3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 UBE2E3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS0000425000 UBE2E3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRIM38 UBE2E3 25348397 N/A physical interaction ComPPI
KLHL42 UBE2E3 25348397 N/A physical interaction ComPPI
UBE2E3 RNF5 14525934 14667819 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
UBE2E3 CHUK 14525934 25348397 9409737 N/A two hybrid,two hybrid ComPPI,HPRD
UBE2E3 ATXN1 14525934 16713569 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
UBE2E3 IPO11 11809816 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
UBE2E3 RNF8 11322894 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
UBE2E3 UBOX5 11274149 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
UBE2E3 SAE1 10187858 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
UBE2E3 ACVR1 14525934 15761153 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
UBE2E3 ARID3A 14525934 15017387 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD
UBE2E3 CNOT4 14525934 15001359 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid ComPPI,HPRD,IntAct
UBE2E3 NFKBIA 10582246 14525934 25348397 9409737 9734360 N/A two hybrid,experimental interaction detection,in vitro,two hybrid ComPPI,HPRD
UBE2E3 RNF14 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 SIAH1 25348397 N/A physical interaction ComPPI
UBE2E3 UFM1 25348397 N/A physical interaction ComPPI
UBE2E3 MUL1 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 CADPS2 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF181 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RMND5B 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF111 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF13 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF130 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF150 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF165 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF167 19690564 23414517 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid fragment pooling approach ComPPI,IntAct
UBE2E3 RNF25 19549727 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF43 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 ZNRF4 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 ZNRF1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF114 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF11 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 DTX3L 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 DZIP3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 TRIM39 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2E3 RNF10 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF185 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2E3 RNF2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 RNF4 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RING1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 DTX3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 CHFR 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 MID1 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBE2E3 MKRN3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RFWD3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 RNF166 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 TRIM2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
UBE2E3 TBL1XR1 25348397 N/A physical interaction ComPPI
UBE2E3 TBL1X 25348397 N/A physical interaction ComPPI
UBE2E3 STUB1 25348397 N/A physical interaction ComPPI
UBE2E3 BRCA1 25348397 N/A physical interaction ComPPI
UBE2E3 MID2 25348397 N/A physical interaction ComPPI
UBE2E3 TRIM27 25348397 N/A physical interaction ComPPI
UBE2E3 TRIM32 25348397 N/A physical interaction ComPPI
UBE2E3 TRIM50 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 TRIM37 25348397 N/A physical interaction ComPPI
UBE2E3 TRIM45 25348397 N/A physical interaction ComPPI
UBE2E3 DDA1 25348397 N/A physical interaction ComPPI
UBE2E3 DET1 25348397 N/A physical interaction ComPPI
UBE2E3 DDB1 25348397 N/A physical interaction ComPPI
UBE2E3 UBA1 25348397 N/A physical interaction ComPPI
UBE2E3 NFE2L2 25348397 N/A physical interaction ComPPI
UBE2E3 UBC 25348397 N/A physical interaction ComPPI
UBE2E3 CUL3 25348397 N/A physical interaction ComPPI
UBE2E3 RCBTB1 25348397 N/A physical interaction ComPPI
UBE2E3 RCBTB2 25348397 N/A physical interaction ComPPI
UBE2E3 SPOP 25348397 N/A physical interaction ComPPI
UBE2E3 CUL1 25348397 N/A physical interaction ComPPI
UBE2E3 CUL4A 25348397 N/A physical interaction ComPPI
UBE2E3 HERC4 25348397 N/A physical interaction ComPPI
UBE2E3 NEDD4L 25348397 N/A physical interaction ComPPI
UBE2E3 WWP2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 ITCH 25348397 N/A physical interaction ComPPI
UBE2E3 BARD1 25348397 N/A physical interaction ComPPI
UBE2E3 MDM2 25348397 N/A physical interaction ComPPI
UBE2E3 HTT 23275563 24234451 25348397 physical association physical interaction,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 TARDBP 25348397 N/A physical interaction ComPPI
UBE2E3 MARCHF5 25348397 N/A physical interaction ComPPI
UBE2E3 RBX1 25348397 N/A physical interaction ComPPI
UBE2E3 RANGAP1 25348397 N/A physical interaction ComPPI
UBE2E3 FBXO25 25348397 N/A physical interaction ComPPI
UBE2E3 CCDC121 25348397 N/A physical interaction ComPPI
UBE2E3 FSD1 25348397 N/A physical interaction ComPPI
UBE2E3 NKD2 25348397 N/A physical interaction ComPPI
UBE2E3 RDH12 25348397 N/A physical interaction ComPPI
UBE2E3 SPRY2 25348397 N/A physical interaction ComPPI
UBE2E3 ETV5 25348397 N/A physical interaction ComPPI
UBE2E3 RC3H2 25348397 N/A physical interaction ComPPI
UBE2E3 OTUB1 24234451 25348397 26752685 association,physical association anti tag coimmunoprecipitation,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 DTL 25348397 N/A physical interaction ComPPI
UBE2E3 PECR 25348397 N/A physical interaction ComPPI
UBE2E3 USP15 25348397 N/A physical interaction ComPPI
UBE2E3 UBB 25348397 N/A physical interaction ComPPI
UBE2E3 RNF220 19549727 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
UBE2E3 TOPORS 25348397 N/A physical interaction ComPPI
UBE2E3 PCGF3 25348397 N/A physical interaction ComPPI
UBE2E3 USP7 25348397 N/A physical interaction ComPPI
UBE2E3 CSNK2A2 25348397 N/A physical interaction ComPPI
UBE2E3 FBRS 25348397 N/A physical interaction ComPPI
UBE2E3 HNRNPL 25348397 N/A physical interaction ComPPI
UBE2E3 PRKN 25348397 N/A physical interaction ComPPI
UBE2E3 PJA1 25348397 N/A physical interaction ComPPI
UBE2E3 UFL1 19690564 24234451 25348397 physical association two hybrid,two hybrid array ComPPI,IntAct
UBE2E3 AUP1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 MAGOH 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 HUWE1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 EEF1A1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 RPL14 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 HERC5 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 UBAP2L 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 UBR5 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 LSM8 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 CEP192 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 ANKRD20A12P 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 ARRDC1 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
UBE2E3 RNF126 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 PICK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 ARRDC3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 TRIM62 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 WBP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
UBE2E3 DAZAP2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RNF115 UBE2E3 19690564 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARIH2 UBE2E3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TGFBR1 UBE2E3 14525934 15761153 N/A experimental interaction detection HPRD
NFKBIA UBE2E3 10187858 10582246 27898060 9409737 9734360 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00008BEA7F UBE2E3 27087310 direct interaction,inhibition N/A NPInter

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