GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
UNC13D
FullNmae
unc-13 homolog D
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:23147
EnsembleID
ENSG00000092929
Uniprot
Q70J99
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
UNC13D
lysosomal_cd
36341760 220 lysosome-dependent cell death genes.
retulator signature
UNC13D
lysosomal_cd
36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
UNC13D
immunogenic
38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
Go Annotation:
GeneSymbol
Go id
UNC13D
GO:0002432,GO:0002467,GO:0005515,GO:0005576,GO:0005764,GO:0005770,GO:0005829,GO:0006909,GO:0016020,GO:0031267,GO:0031267,GO:0033093,GO:0035578,GO:0043231,GO:0043304,GO:0043320,GO:0045921,GO:0046872,GO:0046903,GO:0051607,GO:0055037,GO:0070382,GO:0070382,GO:1900026,GO:1903307
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
UNC13D
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA1
UNC13D
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
GATA2
UNC13D
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
SMARCA4
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
E2F1
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
UNC13D
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000237AF9
UNC13D
18185580
25416803
mrna cleavage,inhibition
array technology
TarBase
URS0000324096
UNC13D
18668040
25416803
mrna cleavage,inhibition
experimental interaction detection
TarBase
URS00003CF1AD
UNC13D
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS0000044FD7
UNC13D
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS000029D9F1
UNC13D
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS00002CEB74
UNC13D
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000355E82
UNC13D
23824327
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
UNC13D
RAB27B
25361965
interaction type
N/A
PTMCode2
RAB27B
UNC13D
25361965
interaction type
N/A
PTMCode2
UNC13D
RAB27A
25361965
interaction type
N/A
PTMCode2
RAB27A
UNC13D
25361965
interaction type
N/A
PTMCode2
Source
Target
Pmid
Interactiontype
Methods
Database
CUL5
UNC13D
25348397
N/A
physical interaction
ComPPI
LMNA
UNC13D
25348397
N/A
two hybrid,physical interaction
ComPPI
VPS37B
UNC13D
25348397
N/A
physical interaction
ComPPI
PICALM
UNC13D
25348397
N/A
physical interaction
ComPPI
XRN2
UNC13D
25348397
N/A
physical interaction
ComPPI
RAB27A
UNC13D
14525934
14699162
25348397
N/A
experimental interaction detection,physical interaction,in vitro,in vivo
ComPPI,HPRD
DPYSL2
UNC13D
25348397
N/A
physical interaction
ComPPI
RAB27B
UNC13D
14525934
14699162
25348397
N/A
experimental interaction detection,in vitro
ComPPI,HPRD
UNC13D
ANXA5
25348397
N/A
physical interaction
ComPPI
UNC13D
AACS
25348397
N/A
physical interaction
ComPPI
UNC13D
G6PD
25348397
N/A
physical interaction
ComPPI
Visualization
